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statisticalmethod
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1
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2
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242
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Detecting genomic signatures of drug resistance breast cancer in transcriptomic data
TransOmicsData
signatureSearchData
StatisticalMethod
written 11 weeks ago by
olusolaxx
• 0
0
votes
1
reply
394
views
Can we compare 3 different experimental conditions with DESeq2?
DESeq2
StatisticalMethod
updated 8 months ago by
swbarnes2
★ 1.4k • written 8 months ago by
Esteban
• 0
0
votes
0
replies
320
views
Job:
Post-Doc: Development of a new method to study the distribution of the effect sizes of QTL
StatisticalMethod
Evolution
QuantitativeTrailLocus
Genetics
JobPosting
8 months ago
pierre.devillemereuil
• 0
0
votes
3
replies
926
views
Differences in differential analysis methods for RNA-Seq
DESeq2
StatisticalMethod
Proteomics
DifferentialExpression
RNASeq
updated 9 months ago by
ATpoint
★ 4.6k • written 9 months ago by
james.zhang20
• 0
2
votes
2
replies
2.3k
views
DESeq2 median of ratios normalization instead of VST or rlog for ordinations?
DESeq2
medianofratiostransformation
StatisticalMethod
Normalization
dispersion
13 months ago
Linton
• 0
1
vote
2
replies
931
views
How to perform longitudinal analysis using EdgeR
StatisticalMethod
FoldChange
edgeR
RNASeq
13 months ago
Sabiha
▴ 20
2
votes
2
replies
753
views
DESeq2: Comparison of single clinical sample to 4 normals using tumour cohort to infer dispersion of single sample
GeneExpression
DESeq2
RNASeqData
RNASeq
StatisticalMethod
14 months ago
Manthos
• 0
5
votes
2
replies
1.5k
views
DecideTest vs topTAGs in edgeR
RNAseq
StatisticalMethod
edgeR
updated 15 months ago by
Gordon Smyth
52k • written 15 months ago by
alvaroperona1
▴ 10
3
votes
2
replies
935
views
Does this RNAseq experiment require a repeated measures approach?
StatisticalMethod
RNASeqData
edgeR
DESeq2
updated 19 months ago by
Gordon Smyth
52k • written 19 months ago by
CDSPARKS
▴ 30
2
votes
3
replies
2.9k
views
deseq2 normalization and statistical method
normalization
deseq2
StatisticalMethod
updated 22 months ago by
ATpoint
★ 4.6k • written 23 months ago by
SH
▴ 10
2
votes
4
replies
1.0k
views
Model comparison in mean-dispersion trend in DESeq2
DESeq2
StatisticalMethod
23 months ago
Loïc
• 0
0
votes
2
replies
1.1k
views
Using Multi-Dimensional Scaling (MDS) to produce a vector in order to account for patient bias when constructing DGE lists from RNA-seq datasets in R?
PrincipalComponent
StatisticalMethod
edgeR
MultidimensionalScaling
Normalization
24 months ago
rcreswell01
• 0
1
vote
3
replies
1.3k
views
Limma-voom with inverse probability weights (similar to sample weights)
limma
limma-voom
StatisticalMethod
updated 2.0 years ago by
Gordon Smyth
52k • written 2.0 years ago by
jay
▴ 10
0
votes
1
reply
693
views
DESeq2 paired multifactor test
DESeq2
StatisticalMethod
updated 2.2 years ago by
Michael Love
43k • written 2.3 years ago by
ijvechetti
▴ 10
0
votes
0
replies
830
views
Job:
Academic position in Non-clinical Biostatistics
JobPosting
StatisticalMethod
2.3 years ago
Laurent Gatto
1.6k
1
vote
2
replies
1.3k
views
Limma adj.p.value the same for many different p.values
limmaGUI
limma
adj.p.value
StatisticalMethod
2.4 years ago
walkerrh95
• 0
0
votes
0
replies
1.1k
views
Job:
Postdoctoral research scientist in computational biology/statistical genetics/functional genomics at Columbia University, USA
Alzheimer's
StatisticalMethod
Genetics
molecularQTL
FunctionalGenomics
2.4 years ago
gaow
• 0
0
votes
0
replies
722
views
Should I adjust p value for multi-levels (groups) and multi-variables?
StatisticalMethod
2.9 years ago
dong
▴ 10
2
votes
3
replies
5.0k
views
Differential gene expression and (adjusted) p-values
edgeR
StatisticalMethod
updated 2.8 years ago by
ruez.richard
• 0 • written 3.0 years ago by
tmms
• 0
6
votes
4
replies
1.3k
views
Limma prametrization
limm
MathematicalBiology
limmaGUI
StatisticalMethod
3.1 years ago
Giovanni
• 0
2
votes
7
replies
1.8k
views
EdgeR, tumor normal pair, no replicatie but multiple patients, to focus on individual patients not combined
edgeR
StatisticalMethod
3.4 years ago
Field -Ye
• 0
0
votes
2
replies
1.8k
views
To retrieve the transcript from gff file with the longest isoform
FunctionalAnnotation
StatisticalMethod
3.6 years ago
Aneesha
• 0
0
votes
1
reply
942
views
DESeq2 Design matrix
StatisticalMethod
DESeq2
updated 3.7 years ago by
Michael Love
43k • written 3.7 years ago by
Saif
• 0
6
votes
6
replies
2.1k
views
limma:arrayWeights() and the "prior.n" parameter for biological replicates? (PROTEOMICS)
Proteomics
limma
StatisticalMethod
updated 3.9 years ago by
Gordon Smyth
52k • written 3.9 years ago by
Steve
▴ 10
1
vote
3
replies
1.4k
views
How to assign random effect factor in DESeq2 desing?
StatisticalMethod
DESeq2
phyloseq
updated 4.0 years ago by
Michael Love
43k • written 4.0 years ago by
zardbid
• 0
0
votes
0
replies
1.5k
views
Why is `scale-free topology` estimated as -sign(slope) * (R^2) in WGCNA?
Network
StatisticalMethod
WGCNA
ExpressionData
4.1 years ago
jol.espinoz
▴ 40
0
votes
2
replies
894
views
p adjusted value not available
StatisticalMethod
DESeq2
updated 4.2 years ago by
Kevin Blighe
★ 4.0k • written 4.2 years ago by
marie
• 0
27 results • Page
1 of 1
Recent ...
Replies
Comment: WGCNA coupled with differential expression analysis: question about baseline mod
by
hetaf16210
• 0
@[slope][1] If feasible, consider conducting both analyses. Start with a pooled analysis to identify broad patterns, then conduct separate …
Comment: DESeq2 adujsted p-value cutoff seemingly not working
by
980linnet
• 0
Stuck on DESeq2 with alpha=.05 for padj cutoff. Can't seem to get the differential expression analysis to stick the landing - it's like try…
Comment: internal error in trio library when trying to use lfmm() in LEA package
by
PW
• 0
>ERROR: unable to open file D://anole_geno.snmf/K1/run1/anole_geno_r1.1.Q. Please, check that the name of the file you provided is correct.…
Comment: DESeq2 adujsted p-value cutoff seemingly not working
by
Guilherme
• 0
Thank you for your answer So the proper way to conduct the analysis is to put the filters in the results() function and later filter the da…
Comment: DiffBind - observation that the default union overlap is actually a gap of 1 bp
by
Ian D.
▴ 70
Please can you comment on this @rory.
Votes
A: how to extract Granges not overlapping with other ganges?
DESeq2 1.20.0 lfcshrink function
A: LIMMA on RT-PCR data
Answer: Efficiently working with HDF5-backed SingleCellExperiments
Efficiently working with HDF5-backed SingleCellExperiments
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ruwaa.ibrahem
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ramiro.barrantes
▴ 10
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Vincent J. Carey, Jr.
6.7k
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Gordon Smyth
52k
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James W. MacDonald
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