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StatisticalMethod
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0
votes
0
replies
82
views
Correlation threshold
MethylationArray
methylationArrayAnalysis
StatisticalMethod
28 days ago
user_bioinfo
• 0
1
vote
2
replies
306
views
Detecting genomic signatures of drug resistance breast cancer in transcriptomic data
TransOmicsData
signatureSearchData
StatisticalMethod
written 5 months ago by
olusolaxx
• 0
0
votes
1
reply
470
views
Can we compare 3 different experimental conditions with DESeq2?
DESeq2
StatisticalMethod
updated 10 months ago by
swbarnes2
★ 1.4k • written 10 months ago by
Esteban
• 0
0
votes
0
replies
388
views
Job:
Post-Doc: Development of a new method to study the distribution of the effect sizes of QTL
StatisticalMethod
Evolution
QuantitativeTrailLocus
Genetics
JobPosting
11 months ago
pierre.devillemereuil
• 0
0
votes
3
replies
1.1k
views
Differences in differential analysis methods for RNA-Seq
DESeq2
StatisticalMethod
Proteomics
DifferentialExpression
RNASeq
updated 11 months ago by
ATpoint
★ 4.8k • written 11 months ago by
james.zhang20
• 0
2
votes
2
replies
3.0k
views
DESeq2 median of ratios normalization instead of VST or rlog for ordinations?
DESeq2
medianofratiostransformation
StatisticalMethod
Normalization
dispersion
15 months ago
Linton
• 0
1
vote
2
replies
1.0k
views
How to perform longitudinal analysis using EdgeR
StatisticalMethod
FoldChange
edgeR
RNASeq
16 months ago
Sabiha
▴ 20
2
votes
2
replies
854
views
DESeq2: Comparison of single clinical sample to 4 normals using tumour cohort to infer dispersion of single sample
GeneExpression
DESeq2
RNASeqData
RNASeq
StatisticalMethod
17 months ago
Manthos
• 0
5
votes
2
replies
1.8k
views
DecideTest vs topTAGs in edgeR
RNAseq
StatisticalMethod
edgeR
updated 18 months ago by
Gordon Smyth
52k • written 18 months ago by
alvaroperona1
▴ 10
3
votes
2
replies
993
views
Does this RNAseq experiment require a repeated measures approach?
StatisticalMethod
RNASeqData
edgeR
DESeq2
updated 22 months ago by
Gordon Smyth
52k • written 22 months ago by
CDSPARKS
▴ 30
2
votes
3
replies
3.2k
views
deseq2 normalization and statistical method
normalization
deseq2
StatisticalMethod
updated 2.1 years ago by
ATpoint
★ 4.8k • written 2.1 years ago by
SH
▴ 10
2
votes
4
replies
1.1k
views
Model comparison in mean-dispersion trend in DESeq2
DESeq2
StatisticalMethod
2.2 years ago
Loïc
• 0
0
votes
2
replies
1.2k
views
Using Multi-Dimensional Scaling (MDS) to produce a vector in order to account for patient bias when constructing DGE lists from RNA-seq datasets in R?
PrincipalComponent
StatisticalMethod
edgeR
MultidimensionalScaling
Normalization
2.2 years ago
rcreswell01
• 0
1
vote
3
replies
1.4k
views
Limma-voom with inverse probability weights (similar to sample weights)
limma
limma-voom
StatisticalMethod
updated 2.2 years ago by
Gordon Smyth
52k • written 2.2 years ago by
jay
▴ 10
0
votes
1
reply
734
views
DESeq2 paired multifactor test
DESeq2
StatisticalMethod
updated 2.4 years ago by
Michael Love
43k • written 2.5 years ago by
ijvechetti
▴ 10
0
votes
0
replies
857
views
Job:
Academic position in Non-clinical Biostatistics
JobPosting
StatisticalMethod
2.5 years ago
Laurent Gatto
1.6k
1
vote
2
replies
1.5k
views
Limma adj.p.value the same for many different p.values
limmaGUI
limma
adj.p.value
StatisticalMethod
2.6 years ago
walkerrh95
• 0
0
votes
0
replies
1.2k
views
Job:
Postdoctoral research scientist in computational biology/statistical genetics/functional genomics at Columbia University, USA
Alzheimer's
StatisticalMethod
Genetics
molecularQTL
FunctionalGenomics
2.6 years ago
gaow
• 0
0
votes
0
replies
757
views
Should I adjust p value for multi-levels (groups) and multi-variables?
StatisticalMethod
3.1 years ago
dong
▴ 10
2
votes
3
replies
5.5k
views
Differential gene expression and (adjusted) p-values
edgeR
StatisticalMethod
updated 3.0 years ago by
ruez.richard
• 0 • written 3.2 years ago by
tmms
• 0
6
votes
4
replies
1.3k
views
Limma prametrization
limm
MathematicalBiology
limmaGUI
StatisticalMethod
3.3 years ago
Giovanni
• 0
2
votes
7
replies
1.9k
views
EdgeR, tumor normal pair, no replicatie but multiple patients, to focus on individual patients not combined
edgeR
StatisticalMethod
3.6 years ago
Field -Ye
• 0
0
votes
2
replies
2.0k
views
To retrieve the transcript from gff file with the longest isoform
FunctionalAnnotation
StatisticalMethod
3.8 years ago
Aneesha
• 0
0
votes
1
reply
1.0k
views
DESeq2 Design matrix
StatisticalMethod
DESeq2
updated 3.9 years ago by
Michael Love
43k • written 3.9 years ago by
Saif
• 0
6
votes
6
replies
2.2k
views
limma:arrayWeights() and the "prior.n" parameter for biological replicates? (PROTEOMICS)
Proteomics
limma
StatisticalMethod
updated 4.1 years ago by
Gordon Smyth
52k • written 4.1 years ago by
Steve
▴ 10
1
vote
3
replies
1.5k
views
How to assign random effect factor in DESeq2 desing?
StatisticalMethod
DESeq2
phyloseq
updated 4.2 years ago by
Michael Love
43k • written 4.2 years ago by
zardbid
• 0
0
votes
0
replies
1.5k
views
Why is `scale-free topology` estimated as -sign(slope) * (R^2) in WGCNA?
Network
StatisticalMethod
WGCNA
ExpressionData
4.3 years ago
jol.espinoz
▴ 40
0
votes
2
replies
942
views
p adjusted value not available
StatisticalMethod
DESeq2
updated 4.4 years ago by
Kevin Blighe
★ 4.0k • written 4.4 years ago by
marie
• 0
28 results • Page
1 of 1
Recent ...
Replies
Comment: How to convert transcript counts to gene counts in R?
by
ben
• 0
Simply summing transcripts by gene is sufficient for use with DESeq2. [sprunki clicker][1] [1]: https://sprunkiclicker.com/
Answer: EuroBioC2024 abstract submission is open!
by
Ali
• 0
[Promo products][1] are a smart way to boost visibility, especially with exciting updates like *News: EuroBioC2024 abstract submission is o…
Answer: ROAST for small sets
by
Gordon Smyth
52k
The p-values from `mroast` will be the same (up to sampling variability associated with random rotations) regardless of whether you test al…
Comment: FlowSOM library requires igraph but igraph does not install
by
Szabolcs
• 0
The R/igraph Installation FAQ covers most issues: https://r.igraph.org/articles/installation-troubleshooting.html
Comment: edgeR::cpm() results in negative values from raw counts of 0
by
Kinnary
▴ 20
Thank you very much for the vis suggestion!
Votes
Answer: ROAST for small sets
Answer: ROAST for small sets
A: conceptual question about FDR, FDR adjusted p-value and q-value
Comment: edgeR::cpm() results in negative values from raw counts of 0
Comment: edgeR::cpm() results in negative values from raw counts of 0
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James W. MacDonald
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