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Comment: Merge Replicates vs Mixed Model
by
abadgerw
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0
Thanks, @gabrielhoffman
The data is actually proteomics so it is intensity data which is why I did not use voom but rather ran ebayes wi…
Comment: ANOVA like approach of edgeR
by
Gordon Smyth
52k
To identify common upregulated or downregulated genes, you would need to test for media condition contrasts for each cell type separately, …
Comment: DESeq2 sizefactors counfounded with biological treatment
by
Anna
•
0
Hi James,
Apologies (re: posting in the wrong place).
Thank you so much for your response, that was exactly the help I needed.
Best,
A…
Comment: ANOVA like approach of edgeR
by
Talip
▴
10
I am comparing the expression patterns of different tissue cell lines (CellType) under five distinct media conditions (Status). Since the c…
Comment: Merge Replicates vs Mixed Model
by
gabriel.hoffman
▴
160
It is almost always better to retain the full observed data, if the statistical software is able to model the repeated measures. This is a…
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