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I noticed the dual populations as well, when using csaw this is controlled for. Regarding the DE profile, given this disease condition we e…
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If you check the underlying code a bit you find that there is a file with data sources:
```r
modes_file <- system.file("extdata", "metadat…
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That plot looks extremely worrying. You have very unbalanced DE profiles and clearly two populations of peaks on the right. I would make su…
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