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Answer: Model performance for spline modelling of RNA-seq timecourses in edgeR
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Gordon Smyth
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I don't understand your question, because there is no difference between limma or glmFit or glmQLFit in terms of spline modeling or the tes…
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Luca
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Perhaps edgeR's upperquartile normalization handles this better, the MA looks a lot more centered at 0
![enter image description here][1]…
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If I assume that Followup gets converted to T3 and Treatment to LowSug somewhere along the line (and therefore GroupTreatment.Followup is G…
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Luca
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I noticed the dual populations as well, when using csaw this is controlled for. Regarding the DE profile, given this disease condition we e…
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ATpoint
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If you check the underlying code a bit you find that there is a file with data sources:
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modes_file <- system.file("extdata", "metadat…
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