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complex-design
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3
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4
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1.4k
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Complicated unbalanced block DOE with partially paired samples and analysis
limma
complex-design
paired design
updated 6.8 years ago by
Aaron Lun
★ 28k • written 6.8 years ago by
ML18
▴ 10
0
votes
5
replies
2.6k
views
getting sample size for RNAseq experiment
rnaseqpower
sspa
sample size
sequencing
complex-design
updated 8.8 years ago by
m.van_iterson
▴ 20 • written 8.9 years ago by
roser.navarro
• 0
9
votes
21
replies
6.0k
views
limma - complex design with paired samples, sex and batch effect
limma
paired samples
complex-design
9.0 years ago • updated 8.9 years ago
aec
▴ 90
7
votes
6
replies
4.3k
views
Design and contrast question limma (additive or nested or duplicateCorrelation())??
limma
model matrix
limma design matrix
complex-design
updated 9.5 years ago by
Aaron Lun
★ 28k • written 9.5 years ago by
Guido Hooiveld
★ 4.1k
1
vote
1
reply
3.1k
views
Factorial Design with DESeq2; contrast problem.
deseq2
multiple factor design
complex-design
updated 9.8 years ago by
Michael Love
43k • written 9.8 years ago by
sifujio
• 0
1
vote
3
replies
7.0k
views
Combat - error - system is computationally singular
combat
software error
rnaseq
complex-design
updated 10.2 years ago by
Peter Langfelder
★ 3.0k • written 10.2 years ago by
Stefano Mangiola
▴ 20
7
votes
11
replies
2.6k
views
Using edgeR on pre-post treatment control design
edgeR
complex-design
updated 10.2 years ago by
James W. MacDonald
67k • written 10.2 years ago by
lwc628
▴ 20
7 results • Page
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Comment: Cross-validation with multiple control subgroups in limma
by
Ali Barry
▴ 40
Thanks so much for taking the time here, the insights are much appreciated. I suspected I'd have to ad hoc compare results if I did repeat …
Answer: Cross-validation with multiple control subgroups in limma
by
Gordon Smyth
52k
limma doesn't do cross-validation or resampling. Like most classical linear modeling procedures in statistics, limma uses a statistical mod…
Comment: Issues with seqlevelsStyle when making custom txdb objects for genomes/annotatio
by
Robert Castelo
★ 3.4k
Hi Hervé, thank you very much for your input into how to properly build and manage TxDb objects. gDNAx has two main inputs, one or more BAM…
Comment: Biostrings: Error writing long reads (>200 kbps) with writeQualityScaledXStringS
by
Aidan
▴ 60
Quick update: this is fixed in a branch awaiting PR to Biostrings (https://github.com/Bioconductor/Biostrings/pull/122). Should be in `deve…
Answer: Can DESeq2's design compensate for sequencing experimental design shortcomings?
by
Michael Love
43k
For statistical analysis plans, I recommend working with a local statistician or someone familiar with linear models in R. I have to reserv…
Votes
C: edgeR and lack of counts ID on CPM matrix
A: DESeq2 Following RSEM
A: importing RSEM data into DESeq2
A: Expected counts from RSEM in DESeq2
A: Using RSEM reads for DESeq2
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