Bioconductor RNA dynamics

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epigenomics RNA methylation RNA dynamics chromatin computational biology Job

7.3 years ago mattia pelizzola ▴ 200

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Answer: Model performance for spline modelling of RNA-seq timecourses in edgeR by Gordon Smyth 52k

I don't understand your question, because there is no difference between limma or glmFit or glmQLFit in terms of spline modeling or the tes…

Comment: [ChIP-seq] DESeq2 on counts matrix from union set of called peaks by Luca • 0

Perhaps edgeR's upperquartile normalization handles this better, the MA looks a lot more centered at 0 ![enter image description here][1]…

Answer: DESeq2 - am I extracting results incorrectly? by James W. MacDonald 68k

If I assume that Followup gets converted to T3 and Treatment to LowSug somewhere along the line (and therefore GroupTreatment.Followup is G…

Comment: [ChIP-seq] DESeq2 on counts matrix from union set of called peaks by Luca • 0

I noticed the dual populations as well, when using csaw this is controlled for. Regarding the DE profile, given this disease condition we e…

Answer: Origin of the labels for the SingleCellMultiModal dataset by ATpoint ★ 4.8k

If you check the underlying code a bit you find that there is a file with data sources: ```r modes_file <- system.file("extdata", "metadat…

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Comment: DESeq - help with pair wise comparisons

Answer: SingleR with multiple single cell references

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