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Batch Correction
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reset
3
votes
3
replies
1.8k
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fastMNN based correction for large multi-run experiment requires a similar population set in all the individual datasets?
scrna-seq
integration
batch correction
updated 4.9 years ago by
Aaron Lun
★ 28k • written 4.9 years ago by
p.joshi
▴ 40
0
votes
1
reply
1.2k
views
Batch correction in Linear Models for methylation data
methylation
ComBat
Linear models
batch correction
AIC
updated 5.0 years ago by
Kevin Blighe
★ 4.0k • written 5.0 years ago by
lucasmiranda42
• 0
5
votes
3
replies
777
views
batch correction in DESeq2 > matrix not full rank > mitigate
DESeq2
batch correction
updated 5.1 years ago by
James W. MacDonald
67k • written 5.1 years ago by
MT
▴ 10
0
votes
3
replies
1.1k
views
Diffbind batch effect blocking error
Diffbind
ATAC
batch correction
blocking factor
updated 5.4 years ago by
Rory Stark
★ 5.2k • written 5.4 years ago by
rm1238
• 0
1
vote
1
reply
1.1k
views
All Pairwise Comparisons with DESeq2 While Controlling for Batch Effects: Does Reference Level Matter?
deseq2
differential expression
batch correction
design
updated 5.5 years ago by
Michael Love
43k • written 5.5 years ago by
wunderl
▴ 40
4
votes
4
replies
1.7k
views
Batch Correction: DESeq2 Linear Model vs Batch-Correction-Specific Algorithms (RUV, ComBat, ect.)
deseq2
differential expression
batch correction
updated 5.5 years ago by
Michael Love
43k • written 5.5 years ago by
wunderl
▴ 40
4
votes
5
replies
2.1k
views
Using SC3 with batch corrected MNN values
SC3
Scater
Scran
scRNA-Seq
Batch Correction
updated 5.7 years ago by
Vladimir Kiselev
▴ 150 • written 5.7 years ago by
hamza_karakurt
▴ 60
7 results • Page
1 of 1
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Comment: Cross-validation with multiple control subgroups in limma
by
Ali Barry
▴ 40
Thanks so much for taking the time here, the insights are much appreciated. I suspected I'd have to ad hoc compare results if I did repeat …
Answer: Cross-validation with multiple control subgroups in limma
by
Gordon Smyth
52k
limma doesn't do cross-validation or resampling. Like most classical linear modeling procedures in statistics, limma uses a statistical mod…
Comment: Issues with seqlevelsStyle when making custom txdb objects for genomes/annotatio
by
Robert Castelo
★ 3.4k
Hi Hervé, thank you very much for your input into how to properly build and manage TxDb objects. gDNAx has two main inputs, one or more BAM…
Comment: Biostrings: Error writing long reads (>200 kbps) with writeQualityScaledXStringS
by
Aidan
▴ 60
Quick update: this is fixed in a branch awaiting PR to Biostrings (https://github.com/Bioconductor/Biostrings/pull/122). Should be in `deve…
Answer: Can DESeq2's design compensate for sequencing experimental design shortcomings?
by
Michael Love
43k
For statistical analysis plans, I recommend working with a local statistician or someone familiar with linear models in R. I have to reserv…
Votes
Comment: Issues with seqlevelsStyle when making custom txdb objects for genomes/annotatio
C: edgeR and lack of counts ID on CPM matrix
A: DESeq2 Following RSEM
A: importing RSEM data into DESeq2
A: Expected counts from RSEM in DESeq2
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Ali Barry
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