Hello!

I have installed Complexheatmap but am receiving the following error when loading the package. Below is my code followed by output.

I tried installing the package "Cairo" and my system says it's installed but I still receive the same error.

Let me know if you need additional information!

> library(ComplexHeatmap)
Error: package or namespace load failed for ‘ComplexHeatmap’:
 .onLoad failed in loadNamespace() for 'Cairo', details:
  call: dyn.load(file, DLLpath = DLLpath, ...)
  error: unable to load shared object '/Library/Frameworks/R.framework/Versions/4.0/Resources/library/Cairo/libs/Cairo.so':
  dlopen(/Library/Frameworks/R.framework/Versions/4.0/Resources/library/Cairo/libs/Cairo.so, 6): Library not loaded: /opt/X11/lib/libXrender.1.dylib
  Referenced from: /Library/Frameworks/R.framework/Versions/4.0/Resources/library/Cairo/libs/Cairo.so
  Reason: image not found

> BiocManager::valid()
[1] TRUE

> traceback()
6: stop(msg, call. = FALSE, domain = NA)
5: value[[3L]](cond)
4: tryCatchOne(expr, names, parentenv, handlers[[1L]])
3: tryCatchList(expr, classes, parentenv, handlers)
2: tryCatch({
       attr(package, "LibPath") <- which.lib.loc
       ns <- loadNamespace(package, lib.loc)
       env <- attachNamespace(ns, pos = pos, deps, exclude, include.only)
   }, error = function(e) {
       P <- if (!is.null(cc <- conditionCall(e))) 
           paste(" in", deparse(cc)[1L])
       else ""
       msg <- gettextf("package or namespace load failed for %s%s:\n %s", 
           sQuote(package), P, conditionMessage(e))
       if (logical.return) 
           message(paste("Error:", msg), domain = NA)
       else stop(msg, call. = FALSE, domain = NA)
   })
1: library(ComplexHeatmap)

> sessionInfo()
R version 4.0.3 (2020-10-10)
Platform: x86_64-apple-darwin17.0 (64-bit)
Running under: macOS Big Sur 10.16

Matrix products: default
LAPACK: /Library/Frameworks/R.framework/Versions/4.0/Resources/lib/libRlapack.dylib

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] grid      stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] Rsubread_2.4.2     forcats_0.5.0      stringr_1.4.0      purrr_0.3.4       
 [5] readr_1.4.0        tidyr_1.1.2        tibble_3.0.4       tidyverse_1.3.0   
 [9] RColorBrewer_1.1-2 dplyr_1.0.2        edgeR_3.32.0       limma_3.46.0      
[13] ggplot2_3.3.3      gplots_3.1.1      

loaded via a namespace (and not attached):
 [1] Rcpp_1.0.5          locfit_1.5-9.4      lubridate_1.7.9.2   lattice_0.20-41    
 [5] png_0.1-7           gtools_3.8.2        assertthat_0.2.1    digest_0.6.27      
 [9] R6_2.5.0            cellranger_1.1.0    backports_1.2.1     reprex_0.3.0       
[13] evaluate_0.14       httr_1.4.2          pillar_1.4.7        rlang_0.4.10       
[17] readxl_1.3.1        rstudioapi_0.13     Matrix_1.3-2        rmarkdown_2.6      
[21] munsell_0.5.0       tinytex_0.28        broom_0.7.3         compiler_4.0.3     
[25] modelr_0.1.8        xfun_0.20           pkgconfig_2.0.3     htmltools_0.5.0    
[29] tidyselect_1.1.0    matrixStats_0.57.0  fansi_0.4.1         crayon_1.3.4       
[33] dbplyr_2.0.0        withr_2.3.0         bitops_1.0-6        jsonlite_1.7.2     
[37] gtable_0.3.0        lifecycle_0.2.0     DBI_1.1.0           magrittr_2.0.1     
[41] scales_1.1.1        KernSmooth_2.23-18  cli_2.2.0           stringi_1.5.3      
[45] fs_1.5.0            xml2_1.3.2          ellipsis_0.3.1      generics_0.1.0     
[49] vctrs_0.3.6         tools_4.0.3         glue_1.4.2          hms_0.5.3          
[53] yaml_2.2.1          colorspace_2.0-0    BiocManager_1.30.10 caTools_1.18.0     
[57] rvest_0.3.6         knitr_1.30          haven_2.3.1

You might need to install XQuartz. I can't confirm, not being a Mac person