WGCNA multiple data sets overlapping analysis
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2323982403 ▴ 60
@2323982403-11356
Last seen 3.7 years ago
Ann Arbor

I was analyzing three data sets using wgcna independently.  Each data set gave me several modules and I want to see their overlapping. With the help of the tutorial "Consensus-RelateToFemMods", I could modify some code to generate a overlapping heatmap containing the overlapped counts and p values.  But when it comes assigning highly overlapped modules in different data sets with the same color, I'm a bit confused.

I'm wondering if there is a function for this reassigning module colors according to overlapping status. If there is not, what kind of rules do I have to follow to write my own code?

wgcna multiple data sets overlap • 2.1k views
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You want to compare how much several networks overlap their modules?

You can only compare between two networks to see the overlapping status. So you would need to compare A with B, B with C and A with C, and then extract your conclusions from there. I recommend a venn diagram of the overlapping modules. 

Another option would be to plot them with color bars and see the resulting image how many sections/genes are predominantly of the same color

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@peter-langfelder-4469
Last seen 8 weeks ago
United States

For pairwise matching, use the function matchLabels. You will want to select one of the three sets as a reference set and match the labels of the other two sets to the reference.
 

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