Greetings!!

can anyone help me with this error encountered and how it can be rectified. is it due to less memory in my system or any other issue

celfiles.gcrma = gcrma(celfiles)
Adjusting for optical effect..
Error: cannot allocate vector of size 124.0 Mb

thanking in anticipation

This is indeed a typical error of having all available RAM exhausted.

Two suggestions:

- perform RMA normalization (instead of gcRMA) [celfiles.rma <- rma(celfiles)]; AFAIK RMA requires less memory.

- if applicable, be sure to run the 64bits version of R. On 64 bit operating systems more memory can be used than on 32 bit OS, thus if possible take advantage of it.