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I have performed deconvolution of GeoMx spatial data using the BayesPrism. The output gene matrix is scaled, and I was wondering if there is anyway to use this data to perform DEG on specific cell populations' gene expression determined by the deconvolution process?
Below is a sample of the scaled data:
DSP-1001660016227-D-A04.dcc DSP-1001660016227-D-A09.dcc DSP-1001660016227-D-A10.dcc
SAMD11 3.1490931 3.2087063 4.8211229
ISG15 -0.2266427 -0.2266427 -0.2266427
AGRN -0.2266427 -0.2266427 -0.2266427
DVL1 -0.2266427 -0.2266427 -0.2266427
MXRA8 3.1490931 3.2087063 3.0001598
ERRFI1 -0.2266427 -0.2266427 -0.2266427
ENO1 3.1490931 3.2087063 4.1266277
PGD 3.1490931 -0.2266427 -0.2266427
PLOD1 5.9765768 5.4783866 3.0001598
TNFRSF1B -0.2266427 -0.2266427 -0.2266427