GenomicDataCommons: Retrieve patient data for RPPA samples
0
0
Entering edit mode
@antonio-miguel-de-jesus-domingues-5182
Last seen 9 months ago
Germany

Hi all,

I am trying to use GenomicDataCommons to retrieve RPPA data and associated patient clinical data for all cancer types in CGD. I am able to find and download the relevant files with:

library("GenomicDataCommons")
library("BiocParallel")
options(MulticoreParam=MulticoreParam(workers=4))

stopifnot(GenomicDataCommons::status()$status=="OK")

ge_manifest <- files() %>%
    filter(type == 'protein_expression') %>%
    filter(access == "open") %>%
    filter(platform == "RPPA") %>%
    manifest()
head(ge_manifest)

fnames <- gdcdata(ge_manifest$id, progress=TRUE)
fnames <- bplapply(ge_manifest$id, gdcdata, progress=FALSE)

rppa_scores <- bplapply(fnames, fread)

But I am not able to figure out how to obtain the clinical data. ge_manifest contains file ids which don't retrieve the patient data, and inside each _RPPA_data.tsv there is no obvious patient id column:

AGID lab_id catalog_number set_id peptide_target protein_expression

Any ideas on how to retrieve the patient data for those samples?

TCGA GenomicDataCommons GDC • 738 views
ADD COMMENT

Login before adding your answer.

Traffic: 769 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6