I have downloaded data from archs rnaseq data. The human hdf5 file (28G). I want to access the expression data and group information. I am using the below code:

h5_exprs <- h5read("archs4_gene_human_v2.1.2.h5", "data/expression")

It throws

Error (scratch_11.R#9): Error in h5checktype(). H5Identifier not valid.

What should I do as extra step to solve the issue?

When I run h5ls("archs4_gene_human_v2.1.2.h5"), the output looks like this:

           group                  name       otype  dclass            dim
0              /                  data   H5I_GROUP                       
1          /data            expression H5I_DATASET INTEGER 620825 x 62548
2              /                  meta   H5I_GROUP                       
3          /meta                 genes   H5I_GROUP                       
4    /meta/genes           gene_symbol H5I_DATASET  STRING          62548
5          /meta               samples   H5I_GROUP                       
6  /meta/samples         aligned_reads H5I_DATASET INTEGER         620825
7  /meta/samples         channel_count H5I_DATASET  STRING         620825
8  /meta/samples   characteristics_ch1 H5I_DATASET  STRING         620825
9  /meta/samples       contact_address H5I_DATASET  STRING         620825
10 /meta/samples          contact_city H5I_DATASET  STRING         620825
11 /meta/samples       contact_country H5I_DATASET  STRING         620825
12 /meta/samples     contact_institute H5I_DATASET  STRING         620825
13 /meta/samples          contact_name H5I_DATASET  STRING         620825
14 /meta/samples           contact_zip H5I_DATASET  STRING         620825
15 /meta/samples       data_processing H5I_DATASET  STRING         620825
16 /meta/samples  extract_protocol_ch1 H5I_DATASET  STRING         620825
17 /meta/samples         geo_accession H5I_DATASET  STRING         620825
18 /meta/samples      instrument_model H5I_DATASET  STRING         620825
19 /meta/samples      last_update_date H5I_DATASET  STRING         620825
20 /meta/samples     library_selection H5I_DATASET  STRING         620825
21 /meta/samples        library_source H5I_DATASET  STRING         620825
22 /meta/samples      library_strategy H5I_DATASET  STRING         620825
23 /meta/samples          molecule_ch1 H5I_DATASET  STRING         620825
24 /meta/samples          organism_ch1 H5I_DATASET  STRING         620825
25 /meta/samples           platform_id H5I_DATASET  STRING         620825
26 /meta/samples              relation H5I_DATASET  STRING         620825
27 /meta/samples             series_id H5I_DATASET  STRING         620825
28 /meta/samples singlecellprobability H5I_DATASET   FLOAT         620825
29 /meta/samples       source_name_ch1 H5I_DATASET  STRING         620825
30 /meta/samples                sra_id H5I_DATASET  STRING         620825
31 /meta/samples                status H5I_DATASET  STRING         620825
32 /meta/samples       submission_date H5I_DATASET  STRING         620825
33 /meta/samples             taxid_ch1 H5I_DATASET  STRING         620825
34 /meta/samples                 title H5I_DATASET  STRING         620825
35 /meta/samples                  type H5I_DATASET  STRING         620825

This question was cross posted and answered at https://stackoverflow.com/questions/75741672/why-reading-group-in-hdf5-in-r-throws-h5identifier-not-valid