Hello,

I am trying to build https://github.com/LTLA/InteractionSet locally but it fails with:

R CMD build .
* checking for file ‘./DESCRIPTION’ ... OK
* preparing ‘InteractionSet’:
* checking DESCRIPTION meta-information ... OK
* cleaning src
* installing the package to build vignettes
* creating vignettes ... ERROR
--- re-building ‘interactions.Rmd’ using rmarkdown
Quitting from lines 64-65 (interactions.Rmd) 
Error: processing vignette 'interactions.Rmd' failed with diagnostics:
trying to generate an object from a virtual class ("DataFrame")
--- failed re-building ‘interactions.Rmd’

SUMMARY: processing the following file failed:
  ‘interactions.Rmd’

Error: Vignette re-building failed.
Execution halted

I faced the problem while trying to build the package on Linux ARM64, but as you can see below it fails the same way on Linux x86_64. The official build seems to be OK: https://bioconductor.org/checkResults/3.17/bioc-LATEST/InteractionSet/ Do I miss some step/prerequisite ? Please let me know if you need more information!

sessionInfo()

# include your problematic code here with any corresponding output 
# please also include the results of running the following in an R session 

R version 4.2.2 Patched (2022-11-10 r83330)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: Ubuntu 22.04.1 LTS

Matrix products: default
BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.10.0
LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.10.0

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
 [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
 [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C            
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

loaded via a namespace (and not attached):
[1] compiler_4.2.2

Why are you using a direct download rather than installing using BiocManager? The InteractionSet package has a set of dependencies, and if your sessionInfo is accurate, you have either not loaded or not installed those dependencies. You evidently don't have S4Vectors installed or loaded, because you are instanciating DataFrame as a virtual class rather than loading the class definitions provided in that package. Whereas if you simply did

library(BiocManager)
install("InteractionSet")

You would get all the dependencies installed, as well as the InteractionSet package