Entering edit mode
Matthias Lienhard
▴
280
@matthias-lienhard-6292
Last seen 10 months ago
Max Planck Institute for molecular Geneā¦
Dear developers of branchpointer,
following the recommendations of a recent review paper on branchpoint prediction tools, we are using branchpointer in the context of alternative splicing. Generally, this works very well, and the results look reasonable. However, we want to follow up on specific effects that seem to affect 3' splice sites with very close branch points, 10-20 bases upstream the AG. Is it possible to tweak branchpointer to score these close branchpoints?
Best, Matthias