SC3 with latent variable corrected counts
1
1
Entering edit mode
Mark ▴ 10
@mark-11758
Last seen 7.8 years ago
Imperial College London

I was just wondering if it's valid to perform SC3 clustering on latent variable normalised counts obtained for example from RUVSeq's RUVg or similar methods?

 

Thanks a lot,

Mark

SC3 single cell • 1.5k views
ADD COMMENT
2
Entering edit mode
@vladimir-kiselev-9342
Last seen 5.6 years ago
Sanger Institute, Cambridge, UK

Hi Mark,

Thanks for your question!

Yes, it is valid. SC3 treats RUV normalised counts the same way as counts normalised by any type of the size factor normalisations.

Cheers,

Vladimir

ADD COMMENT

Login before adding your answer.

Traffic: 811 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6