I have this kind of  data

    genes Foldchange      P.value
1           AK133159   6.746424 1.845362e-02
2           AK132892   6.689709 3.576893e-03
3 ENSMUST00000163068   6.540604 2.632250e-04
4 ENSMUST00000163068   6.540604 2.632250e-04
5         uc007tcs.1   6.214373 3.466160e-07
6           AK006017   5.290344 2.082110e-04

I am running this code to get volcano plot but I have problem that

par(mar=c(3,3,2,1), mgp=c(2,.7,0), tck=-.01)

plot(gene_list$logFC, -log10(gene_list$P.Value),

     xlim=c(-10, 10), ylim=c(0, 15), #Set limits

     xlab="log2 fold change", ylab="-log10 p-value")#Set axis labels

error is like

Error in log10(gene_list$P.Value) : 
  non-numeric argument to mathematical function

Have tried to use str to see that you actually have a numeric column for the p values?

Use

str(yourGeneListObject)

and it will show you what kind of data you have in your columns.

Apart from that if your object and code look exactly as you have typed them here, you have misspelled the P.value column when you call it in your -log10 function.

Cheers