CNV caller software
1
0
Entering edit mode
Bogdan ▴ 670
@bogdan-2367
Last seen 13 months ago
Palo Alto, CA, USA

Dear all,

any suggestions regarding a good algorithm to use to call CNV (copy number variants) in the cancer genomes ? many thanks !

-- bogdan

CNV • 1.4k views
ADD COMMENT
0
Entering edit mode

Using what technology? exome-seq? (still an "open" problem, AFIAK) whole genome sequencing? arrays?

ADD REPLY
0
Entering edit mode
Bogdan ▴ 670
@bogdan-2367
Last seen 13 months ago
Palo Alto, CA, USA

We have been using whole-genome sequencing ;)

ADD COMMENT
0
Entering edit mode

FYI: you should rather post this as a comment as opposed to an answer.

Another question is whether or not you have matched normal samples?

In any event, there are a large number of tools listed on this seqanswers page that you can thumb through.

ADD REPLY
0
Entering edit mode

Thank you Steve. Yes, we have normal-tumor pairs. I looked on the page you sent me the link to, and of course, also in the literature, there are many algorithms. I was just looking for an algorithm that most of the community trusts and the results have been verified. Thank you ;;)

 

ADD REPLY

Login before adding your answer.

Traffic: 885 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6