How to simulate count data to test rnaseq analysis code?
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kjo ▴ 70
@kjo-11078
Last seen 7.9 years ago

All the rnaseq data simulation stuff I've found seems to be based on simulating reads, and applying a full analysis stack to those simulated reads.

I'd prefer to simulate the counts matrix directly.

Is there a package to generate synthetic counts data for testing/comparing rnaseq analysis software?

 

rnaseq_analysis • 1.2k views
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@gordon-smyth
Last seen 11 hours ago
WEHI, Melbourne, Australia

The following link gives complete code for the simulations presented in the voom paper:

  http://bioinf.wehi.edu.au/voom/

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