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sofia.figueiredo
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10
@sofiafigueiredo-11041
Last seen 8.3 years ago
Dear Bioconductor community,
I want to map my FC data to a Pathway using pathview like this:
> pv.out <- pathview(gene.data = Nn.matrix[, 1], gene.idtype = "SYMBOL", pathway.id = "04110", species = "hsa", out.suffix = "Nn", kegg.native = TRUE)
However, I get the following error:
Error in .testForValidKeys(x, keys, keytype, fks) : None of the keys entered are valid keys for 'SYMBOL'. Please use the keys method to see a listing of valid arguments. Note: None of the genes or compounds mapped to the pathway! Argument gene.idtype or cpd.idtype may be wrong.
My gene.data is a matrix, where the rownames are the gene symbol:
> head(Nn.matrix[, 1]) "CISH" "PIM1" "SOCS1" "MTHFD2" "DUSP6" "SLC7A5" 4.4023 2.0829 3.7926 2.1230 3.4521 3.1203
Does anyone know why Pathview is not working in this case? I appreciate your attention.
Thanks in advance,
Sofia
> sessionInfo() R version 3.3.1 (2016-06-21) Platform: x86_64-w64-mingw32/x64 (64-bit) Running under: Windows 7 x64 (build 7601) Service Pack 1 locale: [1] LC_COLLATE=German_Germany.1252 LC_CTYPE=German_Germany.1252 LC_MONETARY=German_Germany.1252 LC_NUMERIC=C [5] LC_TIME=German_Germany.1252 attached base packages: [1] grid stats4 parallel stats graphics grDevices utils datasets methods base other attached packages: [1] KEGGREST_1.12.2 maanova_1.42.0 multtest_2.28.0 [4] factDesign_1.48.0 statmod_1.4.25 mdgsa_1.4.2 [7] plyr_1.8.4 data.table_1.9.6 ComplexHeatmap_1.10.2 [10] vegan_2.4-0 lattice_0.20-33 permute_0.9-0 [13] Heatplus_2.18.0 RColorBrewer_1.1-2 gplots_3.0.1 [16] GO.db_3.3.0 annotate_1.50.0 XML_3.98-1.4 [19] reactome.db_1.55.0 KEGG.db_3.2.3 limma_3.28.19 [22] SCAN.UPC_2.14.0 sva_3.20.0 genefilter_1.54.2 [25] mgcv_1.8-14 nlme_3.1-128 foreach_1.4.3 [28] affyio_1.42.0 affy_1.50.0 GEOquery_2.38.4 [31] hugene20sttranscriptcluster.db_8.4.0 hugene20stprobeset.db_8.4.0 arrayQualityMetrics_3.28.2 [34] pathview_1.12.0 org.Hs.eg.db_3.3.0 AnnotationDbi_1.34.4 [37] GenomicRanges_1.24.2 GenomeInfoDb_1.8.3 pd.hugene.2.0.st_3.14.1 [40] oligo_1.36.1 Biobase_2.32.0 oligoClasses_1.34.0 [43] RSQLite_1.0.0 DBI_0.5 Biostrings_2.40.2 [46] XVector_0.12.1 IRanges_2.6.1 S4Vectors_0.10.3 [49] BiocGenerics_0.18.0 BiocInstaller_1.22.3 loaded via a namespace (and not attached): [1] colorspace_1.2-6 rjson_0.2.15 hwriter_1.3.2 class_7.3-14 modeltools_0.2-21 [6] mclust_5.2 circlize_0.3.8 GlobalOptions_0.0.10 base64_2.0 flexmix_2.3-13 [11] mvtnorm_1.0-5 codetools_0.2-14 splines_3.3.1 robustbase_0.92-6 Formula_1.2-1 [16] Cairo_1.5-9 kernlab_0.9-24 cluster_2.0.4 vsn_3.40.0 png_0.1-7 [21] graph_1.50.0 httr_1.2.1 Matrix_1.2-6 SVGAnnotation_0.93-1 BeadDataPackR_1.24.2 [26] acepack_1.3-3.3 tools_3.3.1 gtable_0.2.0 reshape2_1.4.1 affxparser_1.44.0 [31] Rcpp_0.12.6 trimcluster_0.1-2 RJSONIO_1.3-0 gdata_2.17.0 preprocessCore_1.34.0 [36] setRNG_2013.9-1 iterators_1.0.8 fpc_2.1-10 stringr_1.1.0 affyPLM_1.48.0 [41] gtools_3.5.0 dendextend_1.2.0 DEoptimR_1.0-6 zlibbioc_1.18.0 MASS_7.3-45 [46] scales_0.4.0 SummarizedExperiment_1.2.3 KEGGgraph_1.30.0 beadarray_2.22.2 curl_1.2 [51] gridExtra_2.2.1 ggplot2_2.1.0 rpart_4.1-10 latticeExtra_0.6-28 stringi_1.1.1 [56] gcrma_2.44.0 gridSVG_1.5-0 caTools_1.17.1 shape_1.4.2 chron_2.3-47 [61] prabclus_2.2-6 bitops_1.0-6 bit_1.1-12 magrittr_1.5 R6_2.1.3 [66] Hmisc_3.17-4 whisker_0.3-2 foreign_0.8-66 survival_2.39-5 RCurl_1.95-4.8 [71] nnet_7.3-12 KernSmooth_2.23-15 GetoptLong_0.1.4 Rgraphviz_2.16.0 diptest_0.75-7 [76] xtable_1.8-2 ff_2.2-13 illuminaio_0.14.0 openssl_0.9.4 munsell_0.4.3