gene set (enrichment) analysis
3
0
Entering edit mode
Bogdan ▴ 670
@bogdan-2367
Last seen 14 months ago
Palo Alto, CA, USA

Dear all,

 

please could you advise about the best BioC/R package to use for gene set enrichment analysis ;)

on a side note, may I ask the same question about the easiest package to use for survival analysis :)

many thanks,

-- bogdan

 

 

gsea gsa • 1.9k views
ADD COMMENT
0
Entering edit mode

have you tried the gsea package from the broad institute?

or the gage package 

ADD REPLY
0
Entering edit mode
b.nota ▴ 370
@bnota-7379
Last seen 4.3 years ago
Netherlands

I recommend the GOseq package for GO enrichment analysis, it's quite easy in use if you read the manual first. You only need a list of your significant genes and a list of all your assayed genes.

ADD COMMENT
0
Entering edit mode
Bogdan ▴ 670
@bogdan-2367
Last seen 14 months ago
Palo Alto, CA, USA

thank you !

ADD COMMENT
0
Entering edit mode
Axel Klenk ★ 1.0k
@axel-klenk-3224
Last seen 5 hours ago
UPF, Barcelona, Spain

Dear Bogdan,

I'm a bit late for your question but I think the limma package must be mentioned: see the help pages for camera, roast and romer. These are gene set tests, not enrichment tests, i.e., no DEG list required.

Cheers,

 - axel

 

ADD COMMENT
0
Entering edit mode

thanks Axel !

ADD REPLY

Login before adding your answer.

Traffic: 735 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6