DiffHic package - heatmap generation from normalized data
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@rulicosentino-8154
Last seen 8.9 years ago
Germany

Hi, 

I would like to know how to generate an interaction heatmap, like the one is generated with plotPlaid, after normalizing the input data. More precisely, I would like to generate a heatmap after iterative correction of interaction intensities (correctedContact).

Thanks,

 

 

diffhic • 1.1k views
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Aaron Lun ★ 28k
@alun
Last seen 11 hours ago
The city by the bay

Use plotDI and give it the normalized interaction intensities for each bin pair as fc. It's probably best to log-transform the interaction intensities and rescale them to have a mean of zero, in order to get a sensible visualization. High-intensity interactions will be red, and low-intensity interactions will be blue.

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