Hi,
PSICQUIC is an interesting package. it groups multiple interactomics databases.
Specially reactomeFIs provider displays the DIRECTION of the interaction in column 4 (see sample below). I am seeking for this kind of information.
If PSICQUIC does not have this kind of information, is there an other resource that has it?
Karim
Thanks
head(reactomeFIs)
Gene1 Gene2 Annotation Direction Score
16-5-5 CDC42 predicted - 0.85
16-5-5 PARD3 predicted - 0.92
16-5-5 PARD3B predicted - 0.92
16-5-5 PRKCI predicted - 0.92
16-5-5 PRKCZ predicted - 0.92
16-5-5 RHOJ predicted - 0.85
16-5-5 RHOQ predicted - 0.85
6M1-16 ADRBK2 PPrel: inhibited by, phosphorylated by |- 1.00
6M1-16 ARRB2 PPrel: inhibited by |- 1.00
6M1-16 DKFZP686L0365 PPrel: inhibition -| 1.00
6M1-16 GNAL PPrel: activation -> 1.00
http://reactomews.oicr.on.ca:8080/caBigR3WebApp2014/FIsInGene_121514_with_annotations.txt.zip)
> sessionInfo()
R version 3.2.1 (2015-06-18)
Platform: x86_64-apple-darwin13.4.0 (64-bit)
Running under: OS X 10.10.4 (Yosemite)
but also Kubuntu 14.10