Hi,
probably a silly question but is there a difference between these two models in DESeq2:
counts ~ Condition : Generation
counts ~ Condition * Generation
They both model the interaction between condition and generation, am I correct?
However, when I try to run the upper model, I get an error message:
Error in checkFullRank(modelMatrix) :
the model matrix is not full rank, so the model cannot be fit as specified.
One or more variables or interaction terms in the design formula are linear
combinations of the others and must be removed.
The model with the asterisk works just fine.
Thanks!