tests for equivalence with LIMMA
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@andreas-heider-4538
Last seen 9.8 years ago

Dear BioC community,

is it possible with LIMMA to test for equivalence of expression between two sample groups?

I am thinking about two one sided test (TOST) or double one sided t-test (DOSTT).

I am sure it can be used somewhere, but don't know how. Especially, since one needs the so called "epsilon" to determine the "magnitude of the region of similarity" as written in the documentation of the "equivalence" package. At this moment I am not sure how to calculate a reasonable "epsilon".

 

Hope somebody has had a similar problem, already :-)

 

Thanks in advance,

Andreas

limma differential gene expression equivalence TOST DOSTT • 1.5k views
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@james-w-macdonald-5106
Last seen 2 days ago
United States

There was someone who had a similar problem, just 19 days ago.

extract similar expressed genes (SEGs) rather than DEGs

Rather than opening another thread to rehash the question you already asked, you should simply add to the previous thread.

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