You may try gage package. It has a function, esset.grp, to identify and collapse redundant gene sets. gage can be applied to KEGG pathways, GO and other gene sets. Details at: http://bioconductor.org/packages/release/bioc/html/gage.html http://bioconductor.org/packages/release/bioc/vignettes/gage/inst/doc/gage.pdf -------------------------------------------- On Wed, 1/28/15, Alan Smith [bioc] <noreply@bioconductor.org> wrote: Subject: [bioc] Reduce the redundancy of enriched GO terms To: luo_weijun@yahoo.com Date: Wednesday, January 28, 2015, 2:37 PM Activity on a post you are following on support.bioconductor.org User Alan Smith wrote Question: Reduce the redundancy of enriched GO terms: Hello, I have been using topGO package to find enriched GO terms in DE gene list. Then I would reduce or remove the redundant GO terms using web tool Revigo (http://revigo.irb.hr/). Could someone please point me to a Bioconductor package or a function (if there is one) that I could use to do the same or at least automate submitting list to�Revigo and fetch results in R for differentially expressed gene output. Greatly appreciate your help. Thank you, Alan You may reply via email or visit Reduce the redundancy of enriched GO terms