Extracting normalized intensities
1
0
Entering edit mode
Gene Cutler ▴ 50
@gene-cutler-916
Last seen 10.1 years ago
I'm a little unclear on how to extract normalized intensities from a marrayNorm object. The intensities in maA appear to be the original un-normalized intensities. There are normalization factors in maMloc and maMscale, but I don't know how to apply them. The maMscale look like multiplicative values while the maMloc look additive. Thanks. Gene Cutler Research Investigator Bioinformatics Amgen SF
Normalization Normalization • 834 views
ADD COMMENT
0
Entering edit mode
@jean-yee-hwa-yang-104
Last seen 10.1 years ago
Hi Gene, maM extrat the normalized log-ratios. If you would like to obtain normalized single channel log-intensities. You can simply solve the equations for R and G. M = (R - G) A = (R + G) / 2 Jean On Fri, 24 Sep 2004, Gene Cutler wrote: > I'm a little unclear on how to extract normalized intensities from a > marrayNorm object. The intensities in maA appear to be the original > un-normalized intensities. There are normalization factors in maMloc > and maMscale, but I don't know how to apply them. The maMscale look > like multiplicative values while the maMloc look additive. > > Thanks. > > > > Gene Cutler > Research Investigator > Bioinformatics > Amgen SF > > _______________________________________________ > Bioconductor mailing list > Bioconductor@stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor >
ADD COMMENT

Login before adding your answer.

Traffic: 442 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6