Hello, I have a list of several hundred amino acid change and would like to locate the genomic location for each of them. I also have the transcript ID the amino acid position correspond to. I was wondering if this is possible using GenomicFeatures package? I guess this query is the opposite way that to most annotations for which there is a lot of documentation and tools. Thanks, Dave -- output of sessionInfo(): R version 3.0.3 (2014-03-06) Platform: x86_64-apple-darwin10.8.0 (64-bit) locale: [1] en_GB.UTF-8/en_GB.UTF-8/en_GB.UTF-8/C/en_GB.UTF-8/en_GB.UTF-8 attached base packages: [1] stats graphics grDevices utils datasets methods base > -- Sent via the guest posting facility at bioconductor.org.

Dear Dave, The mapping vignette [1] (in particular the Calculating new coordinates section) from the Pbase package describes what you need, I believe. Best wishes, Laurent [1] http://bioconductor.org/packages/devel/bioc/vignettes/Pbase/inst/d oc/mapping.html > Hello, > I have a list of several hundred amino acid change and would like to > locate the genomic location for each of them. I also have the > transcript ID the amino acid position correspond to. I was wondering if > this is possible using GenomicFeatures package? I guess this query is > the opposite way that to most annotations for which there is a lot of > documentation and tools. > > Thanks, > Dave > > -- output of sessionInfo(): > > R version 3.0.3 (2014-03-06) > Platform: x86_64-apple-darwin10.8.0 (64-bit) > > locale: > [1] en_GB.UTF-8/en_GB.UTF-8/en_GB.UTF-8/C/en_GB.UTF-8/en_GB.UTF-8 > > attached base packages: > [1] stats graphics grDevices utils datasets methods base > > > -- > Sent via the guest posting facility at bioconductor.org. -- Laurent Gatto http://cpu.sysbiol.cam.ac.uk/