I know topTags provides the LR test statistic; and I understand that a value of LR = 0 is a 50-50 chance of being a DEG. But is there a posterior log-odds transformation of the LRT (delta-deviance) value that can be interpreted the same way as limma's B score? My back of the envelop scribble seems to indicate that an LR-based posterior log-odds (given fixed prior proportion p of being a DEG, say 0.01) is: logOdds = logit(p) + LR/2 Yes? Thanks, -Aaron [[alternative HTML version deleted]]