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Stephen Hoang
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30
@stephen-hoang-6156
Last seen 6.9 years ago
Hi All,
Is there a way to identify the genes that contribute to the gene set
enrichments calculated by roast/romer? I realize that all of the genes
in a
given set are contributing to the p-value calculation, but is there a
way
to get at, for example, the genes that contribute to the "PropUp"
value in
the output of roast? And is the analogous gene set knowable in the
case of
romer? I see in roast help page that the "up" and "down" genes are
categorized as such based on a z-score threshold, but what are the
values
in this distribution -- global fold changes, fold changes within a
gene
set, or something else altogether?
Thanks in advance,
Steve
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