Using Biostring to make position frequency matrix
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@fabrice-tourre-4394
Last seen 10.2 years ago
Dear list, There is a PWM function in Biostring to make position weight matrix. How can I make a position frequency matrix with Biostring? Thank you.
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@valerie-obenchain-4275
Last seen 2.8 years ago
United States
Hi, You can use consensusMatrix(). library(Biostrings) data(HNF4alpha) library(BSgenome.Dmelanogaster.UCSC.dm3) chr3R <- Dmelanogaster$chr3R pfm <- consensusMatrix(HNF4alpha) More examples and details on the ?consensusMatrix man page. Valerie On 12/04/2013 04:13 PM, Fabrice Tourre wrote: > Dear list, > > There is a PWM function in Biostring to make position weight matrix. > How can I make a position frequency matrix with Biostring? Thank you. > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor > -- Program in Computational Biology Division of Public Health Sciences Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N, M1-B155 P.O. Box 19024 Seattle, WA 98109-1024 E-mail: vobencha at fhcrc.org Phone: (206) 667-3158 Fax: (206) 667-1319
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Thank you very much. On Thu, Dec 5, 2013 at 12:17 PM, Valerie Obenchain <vobencha at="" fhcrc.org=""> wrote: > Hi, > > You can use consensusMatrix(). > > library(Biostrings) > data(HNF4alpha) > library(BSgenome.Dmelanogaster.UCSC.dm3) > chr3R <- Dmelanogaster$chr3R > pfm <- consensusMatrix(HNF4alpha) > > More examples and details on the ?consensusMatrix man page. > > Valerie > > > On 12/04/2013 04:13 PM, Fabrice Tourre wrote: >> >> Dear list, >> >> There is a PWM function in Biostring to make position weight matrix. >> How can I make a position frequency matrix with Biostring? Thank you. >> >> _______________________________________________ >> Bioconductor mailing list >> Bioconductor at r-project.org >> https://stat.ethz.ch/mailman/listinfo/bioconductor >> Search the archives: >> http://news.gmane.org/gmane.science.biology.informatics.conductor >> > > > -- > Program in Computational Biology > Division of Public Health Sciences > Fred Hutchinson Cancer Research Center > 1100 Fairview Ave. N, M1-B155 > P.O. Box 19024 > Seattle, WA 98109-1024 > > E-mail: vobencha at fhcrc.org > Phone: (206) 667-3158 > Fax: (206) 667-1319
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