POSTDOCTORAL POSITION, reminder - deadline is approaching (September 23, 2012). Position is available either for a computational biologist / bioinformatician or for a molecular biologist to study a role of physical and functional interactions between translation initiation factors and 5' and 3' untranslated regions (UTRs) in a control of mRNA translation and stability. Both canonical and non-canonical translation initiation factors will be in a focus of the study. The main models currently employed in the laboratory are human cell lines - namely derived from various acute leukemia, budding yeast, hepatitis C virus and the beetle Tribolium castaneum. A broad selection of models and used techniques allow us to ask questions ranging from those covering basic functions of translational apparatus to questions concerning associated evolutionary and developmental consequences. Dysregulation of translation initiation and mRNA stability plays a key role in many human pathologies including cancer, leukemia and viral infection. QUALIFICATION AND EXPERIENCE. We are looking for a highly motivated, enthusiastic and qualified researcher who would like to join our team and effort. If computational biologist / bioinformatician, candidate should have, besides basic knowledge of molecular genetics, strong background and interest in computational data analysis, experience with Linux/Unix shell, knowledge in database technologies and solid programming skills. If molecular biologist, candidate should have an experience either in RNA analyses and biochemistry or in cell biology techniques including confocal microscopy, life cell imaging and FRET. Strong communication skills and the ability to interact and co-operate well with other scientists and students in the team are essential. Lab websites: http://web.natur.cuni.cz/~pospisek/, IRESite: http://www.iresite.org/ LOCATION, DEADLINES, ELIGIBILITY, HOW TO APPLY The laboratory is located at Charles University, Prague, Czech republic. The deadline for application is September 23, 2012. Please contact Martin Pospisek at martin at natur.cuni.cz. Only applicants, who received their Ph.D. after March 28, 2008 are eligible. ONLINE ADD http://www.natur.cuni.cz/biology/postdoctoral-position/postdoc-i -- RNDr. Martin Posp??ek, Ph.D. assistant professor Tel.: +420 221 95 1719 E-mail: martin.pospisek at natur.cuni.cz Department of Genetics and Microbiology Charles University in Prague Faculty of Science Vini?n? 5, 128 43 Praha 2 www.natur.cuni.cz/en