Dear Bioconductors, I'm having trouble downloading GSE31014 (or any other study that I tried) from GEO: > library("GEOquery") Setting options('download.file.method.GEOquery'='curl') > options(download.file.method.GEOquery ="wget") > gse <- getGEO(GEO = "GSE31014") Error in function (type, msg, asError = TRUE) : Server denied you to change to the given directory Searching the archive reveals that two years ago a similar problem has been temporary (?) and attributed to server changes at NCBI/GEO. https://stat.ethz.ch/pipermail/bioconductor/2010-March/032095.html Is there a known solution or workaround, or can anyone reproduce the error to confirm the problem is on the server side? Thanks in advance, - axel > traceback() 7: fun(structure(list(message = msg, call = sys.call()), class = c(typeName, "GenericCurlError", "error", "condition"))) 6: function (type, msg, asError = TRUE) { if (!is.character(type)) { i = match(type, CURLcodeValues) typeName = if is.na(i)) character() else names(CURLcodeValues)[i] } typeName = gsub("^CURLE_", "", typeName) fun = (if (asError) stop else warning) fun(structure(list(message = msg, call = sys.call()), class = c(typeName, "GenericCurlError", "error", "condition"))) }(9L, "Server denied you to change to the given directory", TRUE) 5: .Call("R_curl_easy_perform", curl, .opts, isProtected, .encoding, PACKAGE = "RCurl") 4: curlPerform(curl = curl, .opts = opts, .encoding = .encoding) 3: getURL(sprintf(" ftp://ftp.ncbi.nlm.nih.gov/pub/geo/DATA/SeriesMatrix/%s/", GEO)) 2: getAndParseGSEMatrices(GEO, destdir, AnnotGPL = AnnotGPL) 1: getGEO(GEO = "GSE31014") > sessionInfo() R version 2.15.1 (2012-06-22) Platform: x86_64-pc-linux-gnu (64-bit) locale: [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8 [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8 [7] LC_PAPER=C LC_NAME=C [9] LC_ADDRESS=C LC_TELEPHONE=C [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C attached base packages: [1] stats graphics grDevices utils datasets methods base other attached packages: [1] GEOquery_2.23.5 limma_3.12.1 gtools_2.7.0 [4] sfsmisc_1.0-20 geneplotter_1.34.0 lattice_0.20-6 [7] annotate_1.34.1 AnnotationDbi_1.18.1 Biobase_2.16.0 [10] BiocGenerics_0.2.0 MASS_7.3-18 loaded via a namespace (and not attached): [1] compiler_2.15.1 DBI_0.2-5 grid_2.15.1 IRanges_1.14.4 [5] RColorBrewer_1.0-5 RCurl_1.91-1 RSQLite_0.11.1 stats4_2.15.1 [9] tools_2.15.1 XML_3.9-4 xtable_1.7-0 > Axel Klenk Research Informatician Actelion Pharmaceuticals Ltd / Gewerbestrasse 16 / CH-4123 Allschwil / Switzerland The information of this email and in any file transmitted with it is strictly confidential and may be legally privileged. It is intended solely for the addressee. If you are not the intended recipient, any copying, distribution or any other use of this email is prohibited and may be unlawful. In such case, you should please notify the sender immediately and destroy this email. The content of this email is not legally binding unless confirmed by letter. Any views expressed in this message are those of the individual sender, except where the message states otherwise and the sender is authorised to state them to be the views of the sender's company. For further information about Actelion please see our website at http://www.actelion.com