Dear All,
I would like to know the difference between ensembl genes and refseq
genes.
i would appreciate if any one can tell me what is the average
intergenic
distance in both human and mouse??
Any help is appreciated.
Chris.
[[alternative HTML version deleted]]
On Thu, Mar 15, 2012 at 1:50 AM, chris Jhon <cjhon217 at="" gmail.com="">
wrote:
> Dear All,
>
>
> I would like to know the difference between ensembl genes and refseq
genes.
> i would appreciate if any one can tell me what is the average
intergenic
> distance in both human and mouse??
Hi, Chris. You might take a look at the rtracklayer package to get
the refGene and ensgene tracks for human and mouse from UCSC.
Sean
Hi Chris,
On Thursday, March 15, 2012, chris Jhon <cjhon217@gmail.com> wrote:
> Dear All,
>
>
> I would like to know the difference between ensembl genes and refseq
genes.
Refseq annos tend to be more conservative -- I'm not sure how many of
them
are computationally predicted vs. ensembl, for instance.
> i would appreciate if any one can tell me what is the average
intergenic
> distance in both human and mouse??
If I gave you a number, would you believe me? :-)
This is something you can hash out yourself if you get a bit familiar
with
IRanges and GenomicRanges functionality -- then whip up a
GenomicFeatures
TranscriptDb for your two organisms and have a crack at it.
After you do that, report back here with your best guess and the code
you
used to get it ... I'll offer up mine then, too ;-)
-steve
--
Steve Lianoglou
Graduate Student: Computational Systems Biology
| Memorial Sloan-Kettering Cancer Center
| Weill Medical College of Cornell University
Contact Info: http://cbio.mskcc.org/~lianos/contact
[[alternative HTML version deleted]]
Also, in an attempt at being a bit more helpful:
On Thursday, March 15, 2012, Steve Lianoglou
<mailinglist.honeypot@gmail.com>
wrote:
>> i would appreciate if any one can tell me what is the average
intergenic
>> distance in both human and mouse??
>
> If I gave you a number, would you believe me? :-)
>
> This is something you can hash out yourself if you get a bit
familiar
with IRanges and GenomicRanges functionality -- then whip up a
GenomicFeatures TranscriptDb for your two organisms and have a crack
at it.
Off the top of my head, the quick solution I have in mind involves the
`width`, `gaps` and `reduce` functions ... and not necessarily in that
order.
-steve
--
Steve Lianoglou
Graduate Student: Computational Systems Biology
| Memorial Sloan-Kettering Cancer Center
| Weill Medical College of Cornell University
Contact Info: http://cbio.mskcc.org/~lianos/contact
[[alternative HTML version deleted]]