Hi, I have a microarray dataset from Agilent chips. The data were really log ratio between test samples and a universal reference RNA. Because of the nature of log ratios, coefficient of variation (CV) doesn't really apply to this kind of data due to the fact that mean of log ratio is very close to 0. What kind of measurements would people use to measure the dispersion so that I can compare across genes on the chip to find stably expressed genes? something similar to CV would be easily interpreted? Thanks John [[alternative HTML version deleted]]

Hi John, On 2/21/2012 4:44 PM, array chip wrote: > Hi, I have a microarray dataset from Agilent chips. The data were really log ratio between test samples and a universal reference RNA. Because of the nature of log ratios, coefficient of variation (CV) doesn't really apply to this kind of data due to the fact that mean of log ratio is very close to 0. What kind of measurements would people use to measure the dispersion so that I can compare across genes on the chip to find stably expressed genes? something similar to CV would be easily interpreted? Standard deviation. Best, Jim > > Thanks > > John > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor