Hi to all, I have 4 cell lines, 2 in group A and 2 in group B, for which I calculated IC50. I want to know if there is some difference between the 2 groups: a simple t-test seems to me a not correct test for this case. Do you know if exists in DRC package (or in any other package) a more specific test and how to perform it? I checked in manual but I didn't find a solution. Thanks in advance, Andrea

On 11-08-10 02:04 AM, andrea.grilli at ior.it wrote: > Hi to all, > I have 4 cell lines, 2 in group A and 2 in group B, for which I > calculated IC50. > I want to know if there is some difference between the 2 groups: a > simple t-test seems to me a not correct test for this case. Do you know > if exists in DRC package (or in any other package) a more specific test > and how to perform it? I don't know anything about those tests but just wanted to mention that there is no DRC package in Bioconductor (there is a drc pkg on CRAN though...) > I checked in manual but I didn't find a solution. It would probably be helpful to know which manual you checked exactly. Cheers, H. > > Thanks in advance, > Andrea > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor -- Hervé Pagès Program in Computational Biology Division of Public Health Sciences Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N, M1-B514 P.O. Box 19024 Seattle, WA 98109-1024 E-mail: hpages at fhcrc.org Phone: (206) 667-5791 Fax: (206) 667-1319