Hello, In attempting to use gcrma (the beta version of the fast one) I got the following : > Data<-ReadAffy() > eset<-gcrma(Data) Loading required package: hgu133aprobe Loading required package: matchprobes background correction: gcrma normalization: quantiles PM/MM correction : pmonly expression values: medianpolish background correcting...Error: cannot allocate vector of size 8 Kb There were 20 warning messages, each saying : 1: multi-argument returns are deprecated in: return(y = yhat, wt) Any help would be appreciated. Harry Hurd [[alternative HTML version deleted]]