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David Edwards
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@david-edwards-3426
Last seen 10.4 years ago
Applications are invited for the following 3-year PhD position at
Aarhus University, Denmark.
Genomic prediction models are statistical models to predict complex
traits on the basis of genomic data, usually from single nucleotide
polymorphism (SNP) arrays. These models are of central importance in
genomic selection, in which the predictions are used to accelerate
animal and plant breeding programs; they are also important in other
areas, for example, medical genetics. The models are theoretically and
computationally challenging due to the high number of predictor
variables (>50K). To date some of the most successful methods use
Bayesian modelling techniques, in which prior distributions are set on
the SNP effects and other parameters. The goal of this project is to
study whether these models can be improved by taking linkage
disequilibrium (LD) between SNPs into account. Associations between
SNPs induce correlations between SNP effect estimates, and it is hoped
that accounting for LD structure will improve prediction accuracy,
generate more precise estimates of location of large SNP effects, and
improve the computational efficiency of the algorithms.
For more information see
http://agrsci.au.dk/om_djf/jobs/phd_stillinger/
Best Regards
David Edwards
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