question about R package to get gene centric values
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Xiaowei Guan ▴ 90
@xiaowei-guan-4405
Last seen 10.2 years ago
Dear Biodonductor group, I have a question relevant to gene expression dataset. Usually, we will have probes, while a probe set will corresponding to one gene. What should we do about this? Do we use probes as our targets or derive only one value from the probe set corresponding to one gene? Do you know which R package will do this job? Thanks very much for your help. Have a wonderful weekend! best, Xiaowei [[alternative HTML version deleted]]
probe probe • 964 views
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Paul Geeleher ★ 1.3k
@paul-geeleher-2679
Last seen 10.2 years ago
If you're using affy arrays the different affy IDs correspond to different splice variants. If you want to reorganise probes so that there is one gene to one probe google "Brainarray" and that should answer your question. Paul On Fri, Dec 17, 2010 at 10:21 PM, Xiaowei Guan <xxg39 at="" case.edu=""> wrote: > Dear Biodonductor group, > > I have a question relevant to gene expression dataset. Usually, we will have > probes, while a probe set will corresponding to one gene. What should we do > about this? > > Do we use probes as our targets or derive only one value from the probe set > corresponding to one gene? > > Do you know which R package will do this job? Thanks very much for your > help. > > Have a wonderful weekend! > > best, > Xiaowei > > ? ? ? ?[[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor > -- Paul Geeleher School of Mathematics, Statistics and Applied Mathematics National University of Ireland Galway Ireland -- www.bioinformaticstutorials.com
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Thanks Paul, I will try that package. best, Xiaowei On Tue, Dec 21, 2010 at 7:21 AM, Paul Geeleher <paulgeeleher@gmail.com>wrote: > If you're using affy arrays the different affy IDs correspond to > different splice variants. If you want to reorganise probes so that > there is one gene to one probe google "Brainarray" and that should > answer your question. > > Paul > > On Fri, Dec 17, 2010 at 10:21 PM, Xiaowei Guan <xxg39@case.edu> wrote: > > Dear Biodonductor group, > > > > I have a question relevant to gene expression dataset. Usually, we will > have > > probes, while a probe set will corresponding to one gene. What should we > do > > about this? > > > > Do we use probes as our targets or derive only one value from the probe > set > > corresponding to one gene? > > > > Do you know which R package will do this job? Thanks very much for your > > help. > > > > Have a wonderful weekend! > > > > best, > > Xiaowei > > > > [[alternative HTML version deleted]] > > > > _______________________________________________ > > Bioconductor mailing list > > Bioconductor@r-project.org > > https://stat.ethz.ch/mailman/listinfo/bioconductor > > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor > > > > > > -- > Paul Geeleher > School of Mathematics, Statistics and Applied Mathematics > National University of Ireland > Galway > Ireland > -- > www.bioinformaticstutorials.com > [[alternative HTML version deleted]]
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