Hi, I am trying to run affylmGUI on my mac computer. I have already installed the Tlc package as well as Bwidgets through ActiveTcl conversion installing files. However, when running affylmGUI() on R, I keep getting the message below. I have copied the tcl folders from the root library to the user library, and have obtained the same issue. I would really appreciate if you could help me setting this up. Could you please send me an easy guideline to get affylmGUI working? Otherwise, we could use TeamViewer if that would be easier. Kind regards, Lorenzo --------------- Message: Cannot find Tcl/Tk package "BWidget". affylmGUI cannot continue. affylmGUI requires the Tcl/Tk extensions, BWidget and Tktable. You must have Tcl/Tk installed on your computer, The Tcl/Tk installation which comes with R includes BWidget and Tktable. If you do have Tcl/Tk installed elsewhere, including the extensions, make sure that R can find the path to the Tcl library, e.g. C:\Tcl\lib (on Windows) or /usr/lib (on Linux/Unix) or /sw/lib on Mac OSX. Set the environment variable TCL_LIBRARY to the appropriate path. for eg. C:\Tcl\lib\tcl8.4 and set the MY_TCLTK environment variable to a non-empty string, e.g. "Yes". If using Windows, read the R for windows FAQ at http://cran.r-project.org/bin/windows/base/rw-FAQ.html If your Tcl/Tk extensions still can't be found, try addTclPath(""). This could be put in $HOME/.Rprofile If you need further instructions, please contact your system administrator and consider emailing r-help at stat.math.ethz.ch, or browse through the R-help Bioconductor archives for a similar question. Lorenzo Melchor, PhD Mammary Stem Cell Team The Breakthrough Breast Cancer Research Centre (ICR) 237 Fulham Road SW3 6JB lorenzo.melchor at icr.ac.uk The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP. This e-mail message is confidential and for use by the a...{{dropped:2}}