Entering edit mode
Jordi Altirriba Gutiérrez
▴
350
@jordi-altirriba-gutierrez-682
Last seen 5.7 years ago
Dear Bioconductor users,
I am trying to work with CORNA.1.2. package to observe how miRNA
regulates mRNA expression levels, as described in Wu X, Watson M,
CORNA: testing gene lists for regulation by microRNAs, Bioinformatics.
2009 Mar 15;25(6):832-3.
I have downloaded this package from the authors? webpage:
http://corna.sourceforge.net/
Nevertheless, this package was compiled with a version previous than
R.2.10.0, so I am not able to run it in R.2.12.0 version (current
version).
I have downloaded R.2.9.0 version and I am able to load CORNA package
but biomaRt is not running (BioMart web service failed) [sessionInfo
below].
It?s not a problem of BioMart web service, as in R.2.12.0 BioMart is
running correctly.
My questions:
1.- Is there any way to run BioMart in previous versions of R?
(R.2.9.0 or previous)
2.- If it?s not possible, could I recompile CORNA package to run in
R.2.12.0? How?
3.- Is there any other package to associate miRNA expression levels
from microarrays with mRNA expression levels from other microarrays?
(I am working with rats and mice and MMIA is not working with these
species)
Many thanks for your time and suggestions.
Yours faithfully,
Jordi Altirriba
Laboratoire du M?tabolisme
Centre M?dical Universitaire
Geneve
> sessionInfo()
R version 2.9.0 (2009-04-17)
i386-pc-mingw32
locale:
LC_COLLATE=French_Switzerland.1252;LC_CTYPE=French_Switzerland.1252;LC
_MONETARY=French_Switzerland.1252;LC_NUMERIC=C;LC_TIME=French_Switzerl
and.1252
attached base packages:
[1] tools stats graphics grDevices utils datasets
methods base
other attached packages:
[1] CORNA_1.2 XML_2.5-1 GEOquery_2.8.0 RCurl_0.98-1
bitops_1.0-4.1 biomaRt_2.0.0 Biobase_2.4.1