Hi Arne, Thanks for catching this. I'm working on a fix. A temporary workaround for now is to generate smaller DNAStringSet objects and combine them together with c(): > myseq.bs1 <- DNAStringSet(rep(paste(rep("A", 1200), collapse=""), 1000000)) > myseq.bs2 <- DNAStringSet(rep(paste(rep("A", 1200), collapse=""), 1000000)) > myseq.bs <- c(myseq.bs1, myseq.bs2) > myseq.bs A DNAStringSet instance of length 2000000 width seq [1] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [2] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [3] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [4] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [5] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [6] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [7] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [8] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [9] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA ... ... ... [1999992] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999993] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999994] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999995] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999996] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999997] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999998] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999999] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [2000000] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA I'll post here again when I've solved the problem. Cheers, H. On 10/07/2010 09:18 AM, arne.mueller at novartis.com wrote: > Hi, > > sorry, the sequence in my original posting got screwed during copy/paste, > this is the "real" sequence: > >> > CTATGTGTGAGGGCAGCAACCAGAACTGTCTGCCCTGACTTCGCTCAGGATGCTGTGAACATGTGGCT CAGATGGTGCTA > GGCATTTTCCTCTAGAGTCAGAAACGTGGACAGAGAGTCATCTCCTCTGGCTTCCCAGGCATGTCTGC CACTCTGAAGGT > CTGAAGGTCTGGGTCTCCCTCCCATGGGATTTGAGTGCAGAGAGCTGTGTGACTGGGTCCCTTCAGAT CCAGGTGGTGTC > TGGACTGTAGCGTTGAGTGCCCTATCTTCCTGGTCTCAGAGCACCTATACAGTTTCCTCTTGGGCCAG GGATGTGGGCAG > TGGTGGGCTGTACTGGAAGTCTCTCCTGTCCTGCAGTCTCAGGAGTGGCCACCTGTCTGGGTGGTGAG CTCTCTCTCCCA > TGGGGTTAGGGAGCAGGGAGGTTTTGCAAGATTCAGATTTAAGGTCACATTTTATCATCATAATGGAG GACATTAGGAAG > GTCAGAAATAACTCCCTTAAGGAAATACTTGACAACACAAGCAAACTAGTAGAAATCTTTTTAAAAGG AAACACAAAAGT > ATTTTAAAGAATTACAGCAAACCACAACCAAATAGGAGAGGAAATTGAACAAAATCATCCAGGAGTTA AATATGGAAATA > GAAACAATGAAGAGAGCACACAGCGAGACAACCCTGGAGATAGAAAATCTAAGGAAGAGATCAGGAGT CATAGATGCAAG > CATCACTGACGGACTACATGAGATAGAAGAGAGAATTTTGGGAGCAGAAGATATCATAGAAAACATTG ACACAACCTTCA > AAGAGAACGTAAATAGGAAAAAGCTCCTAGCCCTAAACATGCAGGAAATCAGGAAACAAATCAAAGAT CAAACCTAAATA > TATCAGGTATAGAAGAGAGTGAAGACTCCCAACATAAAGGGATGGTAAATATCTTCAACAATATAAAC AATATAAAGGAA > AACATCCCTAACCAAAAGAAATAAATGTCCATAAATAGACATGAAGCCTGCAGAATTCCAAATAGAAT GGACCAGAAAAT > AAATTCCTCCTGTCACATAATAGTCAAAACACCAAATGCACAAAACAAAGAATGAATATTAAAAGCAT TAACGGATAAAG > GTCAAGTACATTTAAAGGCAGACATGTCAGAATTACACCAGAATTCTTACCATGGACTATGAAAGCCA GAAGACAGATGT > > It doesn't matter which sequence one uses to get the DNAStringSet error, > it just has to be long and > there have to be many of them, here's a more generic example: > >> myseq.bs = DNAStringSet(rep(paste(rep("A", 100), collapse=""), 2000)) >> myseq.bs = DNAStringSet(rep(paste(rep("A", 100), collapse=""), 2000000)) >> myseq.bs = DNAStringSet(rep(paste(rep("A", 1200), collapse=""), 2000)) >> myseq.bs = DNAStringSet(rep(paste(rep("A", 1200), collapse=""), > 2000000)) > Error in .Call("new_SharedRaw_from_STRSXP", x, start(solved_SEW), > width(solved_SEW), : > negative length vectors are not allowed > > Arne > > > > > > > arne.mueller at novartis.com > Sent by: bioconductor-bounces at stat.math.ethz.ch > 10/07/2010 05:55 PM > > To > bioconductor at stat.math.ethz.ch > cc > > Subject > [BioC] Biostrings bug? > > > > > > > Dear All, > > I came across the following error in DNAStringSet from the Biostrings > package: > >> myseq = > "CTATGTGTGAGGGCAGCAACCAGAACTGTCTGCCCTGACTTCGCTCAGGATGCTGTGAACATGTGGC TCAGATGGTGCTAGGCATTTTCCTCTAGAGTCAGAAACGTGGACAGAGAGTCATCTCCTCTGGCTTCCCA GGCATGTCTGCCACTCTGAAGGTCTGAAGGTCTGGGTCTCCCTCCCATGGGATTTGAGTGCAGAGAGCTG TGTGACTGGGTCCCTTCAGATCCAGGTGGTGTCTGGACTGTAGCGTTGAGTGCCCTATCTTCCTGGTCTC AGAGCACCTATACAGTTTCCTCTTGGGCCAGGGATGTGGGCAGTGGTGGGCTGTACTGGAAGTCTCTCCT GTCCTGCAGTCTCAGGAGTGGCCACCTGTCTGGGTGGTGAGCTCTCTCTCCCATGGGGTTAGGGAGCAGG GAGGTTTTGCAAGATTCAGATTTAAGGTCACATTTTATCATCATAATGGAGGACATTAGGAAGGTCAGAA ATAACTCCCTTAAGGAAATACTTGACAACACAAGCAAACTAGTAGAAATCTTTTTAAAAGGAAACACAAA AGTATTTTAAAGAATTACAGCAAACCACAACCAAATAGGAGAGGAAATTGAACAAAATCATCCAGGAGTT AAATATGGAAATAGAAACAATGAAGAGAGCACACAGCGAGACAACCCTGGAGATAGAAAATCTAAGGAAG AGATCAGGAGTCATAGATGCAAGCATCACTGACGGACTACATGAGATAGAAGAGAGAATTTTGGGAGCAG AAGATATCATAGAAAACATTGACACAACCTTCAAAGAGAACGTAAATAGGAAAAAGCTCCTAGCCCTAAA CATGCAGGAAATCAGGAAACAAATCAAAGATCAAACCTAAATATATCAGGTATAGAAGAGAGTGAAGACT CCCAACATAAAGGGATGGTAAATATCTTCAACAATATAAACAATATAAAGGAAAACATCCCTAACCAAAA GAAATAAATG T! > > CCATAAATAGACATGAAGCCTGCAGAATTCCAAATAGAATGGACCAGAAAATAAATTCCTCCTGTCAC ATAATAGTCAAAACACCAAATGCACAAAACAAAGAATGAATATTAAAAGCATTAACGGATAAAGGTCAAG TACATTTAAAGGCAGACATGTCAGAATTACACCAGAATTCTTACCATGGACTATGAAAGCCAGAAGACAG ATGT" >> mysDNA = DNAStringSet(myseq) # ok! >> myseq = rep(myseq, 2000000) >> myseq.bs = DNAStringSet(myseq) > Error in .Call("new_SharedRaw_from_STRSXP", x, start(solved_SEW), > width(solved_SEW), : > > negative length vectors are not allowed > > Enter a frame number, or 0 to exit > 1: DNAStringSet(myseq) > 2: XStringSet("DNA", x, start = start, end = end, width = width, use.names > > = u > 3: XStringSet("DNA", x, start = start, end = end, width = width, use.names > > = u > 4: .charToXStringSet(basetype, x, start, end, width, use.names) > 5: .charToXString(basetype, x, solved_SEW) > > Selection: 0 >> > > Strangely the following works ...: > > myseq.bs = c(DNAStringSet(myseq[1:1000000]), > DNAStringSet(myseq[1000001:2000000])) > > Somehow there must be an overflow ... . > > Here's some more info on my system: > >> sessionInfo() > R version 2.11.1 Patched (2010-06-20 r52342) > x86_64-unknown-linux-gnu > > locale: > [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C > [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8 > [5] LC_MONETARY=C LC_MESSAGES=en_US.UTF-8 > [7] LC_PAPER=en_US.UTF-8 LC_NAME=C > [9] LC_ADDRESS=C LC_TELEPHONE=C > [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C > > attached base packages: > [1] stats graphics grDevices datasets utils methods base > > other attached packages: > [1] BSgenome.Rnorvegicus.UCSC.rn4_1.3.16 BSgenome_1.16.4 > [3] Biostrings_2.16.5 GenomicRanges_1.0.3 > [5] IRanges_1.6.11 > > loaded via a namespace (and not attached): > [1] Biobase_2.8.0 tools_2.11.1 > > Linux version 2.6.18-92.el5 (brewbuilder at ls20-bc2-13.build.redhat.com) > (gcc version 4.1.2 20071124 (Red Hat 4.1.2-41)) #1 SMP Tue Apr 29 13:16:15 > > EDT 2008 > > 64 Gb memory > > thanks for your help > +kind regards, > > Arne > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor > > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor -- Hervé Pagès Program in Computational Biology Division of Public Health Sciences Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N, M2-B876 P.O. Box 19024 Seattle, WA 98109-1024 E-mail: hpages at fhcrc.org Phone: (206) 667-5791 Fax: (206) 667-1319

Arne, I completely forgot to check this but I just realize that this has already been addressed in the devel version of Biostrings (which will soon become the new release version). Starting with Biostrings 2.17, a DNAStringSet object can be much bigger: up to 2^31-1 sequences per object and each sequence can itself be up to 2^31-1 letters long (before that the cumulated length of the sequences needed to be <= 2^31-1). So as long as your machine has enough memory (and your OS knows how to make use of that memory), you should be able to create big DNAStringSet objects like this: > myseq.bs = DNAStringSet(rep(paste(rep("A", 1200), collapse=""), 2000000)) > myseq.bs A DNAStringSet instance of length 2000000 width seq [1] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [2] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [3] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [4] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [5] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [6] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [7] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [8] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [9] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA ... ... ... [1999992] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999993] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999994] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999995] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999996] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999997] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999998] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [1999999] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA [2000000] 1200 AAAAAAAAAAAAAAAAAAAAA...AAAAAAAAAAAAAAAAAAAA > sessionInfo() R version 2.12.0 alpha (2010-09-27 r53048) Platform: x86_64-unknown-linux-gnu (64-bit) locale: [1] LC_CTYPE=en_US.utf8 LC_NUMERIC=C [3] LC_TIME=en_US.utf8 LC_COLLATE=en_US.utf8 [5] LC_MONETARY=C LC_MESSAGES=en_US.utf8 [7] LC_PAPER=en_US.utf8 LC_NAME=C [9] LC_ADDRESS=C LC_TELEPHONE=C [11] LC_MEASUREMENT=en_US.utf8 LC_IDENTIFICATION=C attached base packages: [1] stats graphics grDevices utils datasets [6] methods base other attached packages: [1] Biostrings_2.17.47 IRanges_1.7.39 loaded via a namespace (and not attached): [1] Biobase_2.9.2 Note that Biostrings_2.17 and IRanges_1.7 belong to BioC 2.7, the current development version of Bioconductor (which is about to be released). You need R 2.12 (which is about to be released too) if you want to use BioC 2.7. Just use biocLite() from within R-2.12 to install packages. Cheers, H. On 10/07/2010 09:18 AM, arne.mueller at novartis.com wrote: > Hi, > > sorry, the sequence in my original posting got screwed during copy/paste, > this is the "real" sequence: > >> > CTATGTGTGAGGGCAGCAACCAGAACTGTCTGCCCTGACTTCGCTCAGGATGCTGTGAACATGTGGCT CAGATGGTGCTA > GGCATTTTCCTCTAGAGTCAGAAACGTGGACAGAGAGTCATCTCCTCTGGCTTCCCAGGCATGTCTGC CACTCTGAAGGT > CTGAAGGTCTGGGTCTCCCTCCCATGGGATTTGAGTGCAGAGAGCTGTGTGACTGGGTCCCTTCAGAT CCAGGTGGTGTC > TGGACTGTAGCGTTGAGTGCCCTATCTTCCTGGTCTCAGAGCACCTATACAGTTTCCTCTTGGGCCAG GGATGTGGGCAG > TGGTGGGCTGTACTGGAAGTCTCTCCTGTCCTGCAGTCTCAGGAGTGGCCACCTGTCTGGGTGGTGAG CTCTCTCTCCCA > TGGGGTTAGGGAGCAGGGAGGTTTTGCAAGATTCAGATTTAAGGTCACATTTTATCATCATAATGGAG GACATTAGGAAG > GTCAGAAATAACTCCCTTAAGGAAATACTTGACAACACAAGCAAACTAGTAGAAATCTTTTTAAAAGG AAACACAAAAGT > ATTTTAAAGAATTACAGCAAACCACAACCAAATAGGAGAGGAAATTGAACAAAATCATCCAGGAGTTA AATATGGAAATA > GAAACAATGAAGAGAGCACACAGCGAGACAACCCTGGAGATAGAAAATCTAAGGAAGAGATCAGGAGT CATAGATGCAAG > CATCACTGACGGACTACATGAGATAGAAGAGAGAATTTTGGGAGCAGAAGATATCATAGAAAACATTG ACACAACCTTCA > AAGAGAACGTAAATAGGAAAAAGCTCCTAGCCCTAAACATGCAGGAAATCAGGAAACAAATCAAAGAT CAAACCTAAATA > TATCAGGTATAGAAGAGAGTGAAGACTCCCAACATAAAGGGATGGTAAATATCTTCAACAATATAAAC AATATAAAGGAA > AACATCCCTAACCAAAAGAAATAAATGTCCATAAATAGACATGAAGCCTGCAGAATTCCAAATAGAAT GGACCAGAAAAT > AAATTCCTCCTGTCACATAATAGTCAAAACACCAAATGCACAAAACAAAGAATGAATATTAAAAGCAT TAACGGATAAAG > GTCAAGTACATTTAAAGGCAGACATGTCAGAATTACACCAGAATTCTTACCATGGACTATGAAAGCCA GAAGACAGATGT > > It doesn't matter which sequence one uses to get the DNAStringSet error, > it just has to be long and > there have to be many of them, here's a more generic example: > >> myseq.bs = DNAStringSet(rep(paste(rep("A", 100), collapse=""), 2000)) >> myseq.bs = DNAStringSet(rep(paste(rep("A", 100), collapse=""), 2000000)) >> myseq.bs = DNAStringSet(rep(paste(rep("A", 1200), collapse=""), 2000)) >> myseq.bs = DNAStringSet(rep(paste(rep("A", 1200), collapse=""), > 2000000)) > Error in .Call("new_SharedRaw_from_STRSXP", x, start(solved_SEW), > width(solved_SEW), : > negative length vectors are not allowed > > Arne > > > > > > > arne.mueller at novartis.com > Sent by: bioconductor-bounces at stat.math.ethz.ch > 10/07/2010 05:55 PM > > To > bioconductor at stat.math.ethz.ch > cc > > Subject > [BioC] Biostrings bug? > > > > > > > Dear All, > > I came across the following error in DNAStringSet from the Biostrings > package: > >> myseq = > "CTATGTGTGAGGGCAGCAACCAGAACTGTCTGCCCTGACTTCGCTCAGGATGCTGTGAACATGTGGC TCAGATGGTGCTAGGCATTTTCCTCTAGAGTCAGAAACGTGGACAGAGAGTCATCTCCTCTGGCTTCCCA GGCATGTCTGCCACTCTGAAGGTCTGAAGGTCTGGGTCTCCCTCCCATGGGATTTGAGTGCAGAGAGCTG TGTGACTGGGTCCCTTCAGATCCAGGTGGTGTCTGGACTGTAGCGTTGAGTGCCCTATCTTCCTGGTCTC AGAGCACCTATACAGTTTCCTCTTGGGCCAGGGATGTGGGCAGTGGTGGGCTGTACTGGAAGTCTCTCCT GTCCTGCAGTCTCAGGAGTGGCCACCTGTCTGGGTGGTGAGCTCTCTCTCCCATGGGGTTAGGGAGCAGG GAGGTTTTGCAAGATTCAGATTTAAGGTCACATTTTATCATCATAATGGAGGACATTAGGAAGGTCAGAA ATAACTCCCTTAAGGAAATACTTGACAACACAAGCAAACTAGTAGAAATCTTTTTAAAAGGAAACACAAA AGTATTTTAAAGAATTACAGCAAACCACAACCAAATAGGAGAGGAAATTGAACAAAATCATCCAGGAGTT AAATATGGAAATAGAAACAATGAAGAGAGCACACAGCGAGACAACCCTGGAGATAGAAAATCTAAGGAAG AGATCAGGAGTCATAGATGCAAGCATCACTGACGGACTACATGAGATAGAAGAGAGAATTTTGGGAGCAG AAGATATCATAGAAAACATTGACACAACCTTCAAAGAGAACGTAAATAGGAAAAAGCTCCTAGCCCTAAA CATGCAGGAAATCAGGAAACAAATCAAAGATCAAACCTAAATATATCAGGTATAGAAGAGAGTGAAGACT CCCAACATAAAGGGATGGTAAATATCTTCAACAATATAAACAATATAAAGGAAAACATCCCTAACCAAAA GAAATAAATG T! > > CCATAAATAGACATGAAGCCTGCAGAATTCCAAATAGAATGGACCAGAAAATAAATTCCTCCTGTCAC ATAATAGTCAAAACACCAAATGCACAAAACAAAGAATGAATATTAAAAGCATTAACGGATAAAGGTCAAG TACATTTAAAGGCAGACATGTCAGAATTACACCAGAATTCTTACCATGGACTATGAAAGCCAGAAGACAG ATGT" >> mysDNA = DNAStringSet(myseq) # ok! >> myseq = rep(myseq, 2000000) >> myseq.bs = DNAStringSet(myseq) > Error in .Call("new_SharedRaw_from_STRSXP", x, start(solved_SEW), > width(solved_SEW), : > > negative length vectors are not allowed > > Enter a frame number, or 0 to exit > 1: DNAStringSet(myseq) > 2: XStringSet("DNA", x, start = start, end = end, width = width, use.names > > = u > 3: XStringSet("DNA", x, start = start, end = end, width = width, use.names > > = u > 4: .charToXStringSet(basetype, x, start, end, width, use.names) > 5: .charToXString(basetype, x, solved_SEW) > > Selection: 0 >> > > Strangely the following works ...: > > myseq.bs = c(DNAStringSet(myseq[1:1000000]), > DNAStringSet(myseq[1000001:2000000])) > > Somehow there must be an overflow ... . > > Here's some more info on my system: > >> sessionInfo() > R version 2.11.1 Patched (2010-06-20 r52342) > x86_64-unknown-linux-gnu > > locale: > [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C > [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8 > [5] LC_MONETARY=C LC_MESSAGES=en_US.UTF-8 > [7] LC_PAPER=en_US.UTF-8 LC_NAME=C > [9] LC_ADDRESS=C LC_TELEPHONE=C > [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C > > attached base packages: > [1] stats graphics grDevices datasets utils methods base > > other attached packages: > [1] BSgenome.Rnorvegicus.UCSC.rn4_1.3.16 BSgenome_1.16.4 > [3] Biostrings_2.16.5 GenomicRanges_1.0.3 > [5] IRanges_1.6.11 > > loaded via a namespace (and not attached): > [1] Biobase_2.8.0 tools_2.11.1 > > Linux version 2.6.18-92.el5 (brewbuilder at ls20-bc2-13.build.redhat.com) > (gcc version 4.1.2 20071124 (Red Hat 4.1.2-41)) #1 SMP Tue Apr 29 13:16:15 > > EDT 2008 > > 64 Gb memory > > thanks for your help > +kind regards, > > Arne > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor > > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor -- Hervé Pagès Program in Computational Biology Division of Public Health Sciences Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N, M2-B876 P.O. Box 19024 Seattle, WA 98109-1024 E-mail: hpages at fhcrc.org Phone: (206) 667-5791 Fax: (206) 667-1319