We are pleased to announce CRdata.org, a free open-source menu-driven file-sharing and Cloud-Computing web-service for R & Bioconductor users. CRdata gives people without R expertise an intuitive graphical interface to R/Bioconductor, while R experts can use CRdata to share their algorithms with non-experts, and to manage shared Cloud Computing resources for multiple user groups. Using CRdata, you can: * Run your data analysis and modeling R scripts in the Cloud -No need to buy or maintain a local CPU cluster. -No need to install/maintain R and BioConductor. CRdata automatically updates its R and Bioconductor libraries. -Minimize costs by using on-demand Cloud Computing resources. * Share your data & scripts with your collaborators (or the world) -You can choose who you share your data and/or scripts with. -CRdata provides an intuitive GUI interface to your scripts. -Analysis results are saved as files and persistent HTML web pages. * Make your publications easier to explore and reproduce -Deposit your paper's data, analysis methods, and models in CRdata. -CRdata provides user-ratings, usage-tracking and feedback tools. * Provide tailored data & analysis resources to subscribers -Create CRdata Special Interest Groups with shared resources. * Share classroom exercise scripts and data with your students -Put your instructions and notes into your CRdata HTML Help files. If you are a programmer, we encourage you to download the CRdata (Ruby on Rails) source code and extend it, for example to provide: * Private instances of CRdata behind firewalls. * Analysis resources via cell phones. * Access to languages and analysis environments other than R. * Computation on processor nodes other than the Amazon Cloud. * CRdata resources integrated into 3rd party software. * Data aggregation and filtering web services. CRdata was developed in the Division of Biology at the California Instittue of Technology by Rajiv Dulepet, Michael Angerman and Hamid Bolouri as part of a collaboration with the laboratory of Dr. Ellen Rothenberg (Caltech), with code contributions by SparkTech Software, and Bioconductor contributions by Dr. Martin Morgan of the Fred Hutchinson Cancer Research Center. The development of this free, open-source community resource was supported in part by NHLBI grant number HL089102 to Hamid Bolouri. The CRdata Development Team (http://crdata.org/about)