Memory and vector size management on linux 64bit
1
0
Entering edit mode
@manca-marco-path-3578
Last seen 10.3 years ago
Dear fellow bioconductors, good afternoon. I am encountering an error concerning the allocations of vectors bigger than a certain size. My problem is that said size is far below the amount of RAM I have installed on the system. Following some previous threads on the topic I have at first thought that my RAM could have been temporarily unavailable thus I have monitored the memory usage and the error message appeared when just 2,5Gb were in use out of the about 7 Gb available. The system is running linux Ubuntu Hardy Heron 64bit, and it sports a Xeon CPU and 8Gb of RAM. Following I am pasting my code and my sessionInfo() # Charging my microArray data (44 human whole genome by Illumina) >library(lumi) >fileName <- "MyExperiment_no_32_no_tech_duplos.csv"; >library(lumiHumanAll.db) >Data.Immature <- lumiR(fileName, lib="lumiHumanAll.db"); >Data <- lumiExpresso(Data.Immature, QC.evaluation=TRUE); # Extract expression data from lumi object: >Expression <- exprs(Data) >names(Expression) <- Data at phenoData@data$sampleID # Calculate distance matrix for cluster analysis >distance=dist(Expression, method="euclidean") Error: cannot allocate vector of size 1.8 Gb > sessionInfo() R version 2.10.1 (2009-12-14) i486-pc-linux-gnu locale: [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8 [5] LC_MONETARY=C LC_MESSAGES=en_US.UTF-8 [7] LC_PAPER=en_US.UTF-8 LC_NAME=C [9] LC_ADDRESS=C LC_TELEPHONE=C [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C attached base packages: [1] stats graphics grDevices utils datasets methods base other attached packages: [1] lumiHumanAll.db_1.8.1 org.Hs.eg.db_2.3.6 lumi_1.12.4 [4] MASS_7.3-5 RSQLite_0.8-3 DBI_0.2-5 [7] preprocessCore_1.8.0 mgcv_1.6-1 affy_1.24.2 [10] annotate_1.24.1 AnnotationDbi_1.8.1 Biobase_2.6.1 loaded via a namespace (and not attached): [1] affyio_1.14.0 grid_2.10.1 lattice_0.18-3 Matrix_0.999375-37 [5] nlme_3.1-96 tools_2.10.1 xtable_1.5-6 Reading this page ( http://stat.ethz.ch/R-manual/R-patched/library/base/html/Memory.html ) I have come to hypothesize that there could be some vector size limit indipendent from the RAM availability, but I wonder whether it is true on a 64bit machine and how could I circumvent the problem: 1) any suggestion on how to modify the vector size threshold (if it exists)? 2) any suggestion on how to force the dist function to strip down the matrix into smaller vectors? Thank you in advance for your attention and for any feedback. All the best, Marco -- Marco Manca, MD University of Maastricht Faculty of Health, Medicine and Life Sciences (FHML) Cardiovascular Research Institute (CARIM) Mailing address: PO Box 616, 6200 MD Maastricht (The Netherlands) Visiting address: Experimental Vascular Pathology group, Dept of Pathology - Room5.08, Maastricht University Medical Center, P. Debeijelaan 25, 6229 HX Maastricht E-mail: m.manca at path.unimaas.nl Office telephone: +31(0)433874633 Personal mobile: +31(0)626441205 Twitter: @markomanka ********************************************************************** *********************************************** This email and any files transmitted with it are confide...{{dropped:15}}
Microarray lumi Microarray lumi • 1.2k views
ADD COMMENT
0
Entering edit mode
@benilton-carvalho-1375
Last seen 4.8 years ago
Brazil/Campinas/UNICAMP
what do you get when you run: .Machine[["sizeof.pointer"]] ? I'm really surprised by the "i486-pc-linux-gnu" bit from your sessionInfo()... I'd expect something like x86_64, if you were running a 64 bit version of R. Given that you're running Ubuntu, you're expected to follow the steps as described by the page below: http://cran.ma.imperial.ac.uk/bin/linux/ubuntu/ b On Fri, Apr 16, 2010 at 5:30 PM, Manca Marco (PATH) <m.manca at="" path.unimaas.nl=""> wrote: > > Dear fellow bioconductors, > > good afternoon. > > I am encountering an error concerning the allocations of vectors bigger than a certain size. My problem is that said size is far below the amount of RAM I have installed on the system. > > Following some previous threads on the topic I have at first thought that my RAM could have been temporarily unavailable thus I have monitored the memory usage and the error message appeared when just 2,5Gb were in use out of the about 7 Gb available. > > The system is running linux Ubuntu Hardy Heron 64bit, and it sports a Xeon CPU and 8Gb of RAM. > > Following I am pasting my code and my sessionInfo() > > # Charging my microArray data (44 human whole genome by Illumina) >>library(lumi) >>fileName <- "MyExperiment_no_32_no_tech_duplos.csv"; >>library(lumiHumanAll.db) >>Data.Immature <- lumiR(fileName, lib="lumiHumanAll.db"); >>Data <- lumiExpresso(Data.Immature, QC.evaluation=TRUE); > > # Extract expression data from lumi object: >>Expression <- exprs(Data) >>names(Expression) <- Data at phenoData@data$sampleID > > # Calculate distance matrix for cluster analysis >>distance=dist(Expression, method="euclidean") > Error: cannot allocate vector of size 1.8 Gb > >> sessionInfo() > R version 2.10.1 (2009-12-14) > i486-pc-linux-gnu > > locale: > ?[1] LC_CTYPE=en_US.UTF-8 ? ? ? LC_NUMERIC=C > ?[3] LC_TIME=en_US.UTF-8 ? ? ? ?LC_COLLATE=en_US.UTF-8 > ?[5] LC_MONETARY=C ? ? ? ? ? ? ?LC_MESSAGES=en_US.UTF-8 > ?[7] LC_PAPER=en_US.UTF-8 ? ? ? LC_NAME=C > ?[9] LC_ADDRESS=C ? ? ? ? ? ? ? LC_TELEPHONE=C > [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C > > attached base packages: > [1] stats ? ? graphics ?grDevices utils ? ? datasets ?methods ? base > > other attached packages: > ?[1] lumiHumanAll.db_1.8.1 org.Hs.eg.db_2.3.6 ? ?lumi_1.12.4 > ?[4] MASS_7.3-5 ? ? ? ? ? ?RSQLite_0.8-3 ? ? ? ? DBI_0.2-5 > ?[7] preprocessCore_1.8.0 ?mgcv_1.6-1 ? ? ? ? ? ?affy_1.24.2 > [10] annotate_1.24.1 ? ? ? AnnotationDbi_1.8.1 ? Biobase_2.6.1 > > loaded via a namespace (and not attached): > [1] affyio_1.14.0 ? ? ?grid_2.10.1 ? ? ? ?lattice_0.18-3 ? ? Matrix_0.999375-37 > [5] nlme_3.1-96 ? ? ? ?tools_2.10.1 ? ? ? xtable_1.5-6 > > > > Reading this page ( http://stat.ethz.ch/R-manual/R-patched/library/base/html/Memory.html ) I have come to hypothesize that there could be some vector size limit indipendent from the RAM availability, but I wonder whether it is true on a 64bit machine and how ?could I circumvent ?the problem: > > 1) any suggestion on how to modify the vector size threshold (if it exists)? > > 2) any suggestion on how to force the dist function to strip ?down the matrix into smaller vectors? > > > Thank you in advance for your attention and for any feedback. > > All the best, Marco > > > -- > Marco Manca, MD > University of Maastricht > Faculty of Health, Medicine and Life Sciences (FHML) > Cardiovascular Research Institute (CARIM) > > Mailing address: PO Box 616, 6200 MD Maastricht (The Netherlands) > Visiting address: Experimental Vascular Pathology group, Dept of Pathology - Room5.08, ?Maastricht University Medical Center, P. Debeijelaan 25, 6229 ?HX Maastricht > > E-mail: m.manca at path.unimaas.nl > Office telephone: +31(0)433874633 > Personal mobile: +31(0)626441205 > Twitter: @markomanka > > > ******************************************************************** ************************************************* > > This email and any files transmitted with it are confide...{{dropped:15}} > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor >
ADD COMMENT
0
Entering edit mode
Dear Benilton, thank you for the prompt reply. I suspect you are right. R had just been installed from the Canonical repository on this machine and it was a 32bit edition. Thank you for your suggestion and for pointing out the 64bit repositories. Just for the sake of completeness at this point, since you alread solved the puzzle, I attach the output of the command you suggested: > .Machine[["sizeof.pointer"]] [1] 4 All the best, Marco -- Marco Manca, MD University of Maastricht Faculty of Health, Medicine and Life Sciences (FHML) Cardiovascular Research Institute (CARIM) Mailing address: PO Box 616, 6200 MD Maastricht (The Netherlands) Visiting address: Experimental Vascular Pathology group, Dept of Pathology - Room5.08, Maastricht University Medical Center, P. Debeijelaan 25, 6229 HX Maastricht E-mail: m.manca at path.unimaas.nl Office telephone: +31(0)433874633 Personal mobile: +31(0)626441205 Twitter: @markomanka ********************************************************************** *********************************************** This email and any files transmitted with it are confidential and solely for the use of the intended recipient. It may contain material protected by privacy or attorney-client privilege. If you are not the intended recipient or the person responsible for delivering to the intended recipient, be advised that you have received this email in error and that any use is STRICTLY PROHIBITED. If you have received this email in error please notify us by telephone on +31626441205 Dr Marco MANCA ********************************************************************** *********************************************** ________________________________________ Da: Benilton Carvalho [beniltoncarvalho at gmail.com] Inviato: venerd? 16 aprile 2010 18.47 A: Manca Marco (PATH) Cc: bioconductor mailing list Oggetto: Re: [BioC] Memory and vector size management on linux 64bit what do you get when you run: .Machine[["sizeof.pointer"]] ? I'm really surprised by the "i486-pc-linux-gnu" bit from your sessionInfo()... I'd expect something like x86_64, if you were running a 64 bit version of R. Given that you're running Ubuntu, you're expected to follow the steps as described by the page below: http://cran.ma.imperial.ac.uk/bin/linux/ubuntu/ b On Fri, Apr 16, 2010 at 5:30 PM, Manca Marco (PATH) <m.manca at="" path.unimaas.nl=""> wrote: > > Dear fellow bioconductors, > > good afternoon. > > I am encountering an error concerning the allocations of vectors bigger than a certain size. My problem is that said size is far below the amount of RAM I have installed on the system. > > Following some previous threads on the topic I have at first thought that my RAM could have been temporarily unavailable thus I have monitored the memory usage and the error message appeared when just 2,5Gb were in use out of the about 7 Gb available. > > The system is running linux Ubuntu Hardy Heron 64bit, and it sports a Xeon CPU and 8Gb of RAM. > > Following I am pasting my code and my sessionInfo() > > # Charging my microArray data (44 human whole genome by Illumina) >>library(lumi) >>fileName <- "MyExperiment_no_32_no_tech_duplos.csv"; >>library(lumiHumanAll.db) >>Data.Immature <- lumiR(fileName, lib="lumiHumanAll.db"); >>Data <- lumiExpresso(Data.Immature, QC.evaluation=TRUE); > > # Extract expression data from lumi object: >>Expression <- exprs(Data) >>names(Expression) <- Data at phenoData@data$sampleID > > # Calculate distance matrix for cluster analysis >>distance=dist(Expression, method="euclidean") > Error: cannot allocate vector of size 1.8 Gb > >> sessionInfo() > R version 2.10.1 (2009-12-14) > i486-pc-linux-gnu > > locale: > [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C > [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8 > [5] LC_MONETARY=C LC_MESSAGES=en_US.UTF-8 > [7] LC_PAPER=en_US.UTF-8 LC_NAME=C > [9] LC_ADDRESS=C LC_TELEPHONE=C > [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C > > attached base packages: > [1] stats graphics grDevices utils datasets methods base > > other attached packages: > [1] lumiHumanAll.db_1.8.1 org.Hs.eg.db_2.3.6 lumi_1.12.4 > [4] MASS_7.3-5 RSQLite_0.8-3 DBI_0.2-5 > [7] preprocessCore_1.8.0 mgcv_1.6-1 affy_1.24.2 > [10] annotate_1.24.1 AnnotationDbi_1.8.1 Biobase_2.6.1 > > loaded via a namespace (and not attached): > [1] affyio_1.14.0 grid_2.10.1 lattice_0.18-3 Matrix_0.999375-37 > [5] nlme_3.1-96 tools_2.10.1 xtable_1.5-6 > > > > Reading this page ( http://stat.ethz.ch/R-manual/R-patched/library/base/html/Memory.html ) I have come to hypothesize that there could be some vector size limit indipendent from the RAM availability, but I wonder whether it is true on a 64bit machine and how could I circumvent the problem: > > 1) any suggestion on how to modify the vector size threshold (if it exists)? > > 2) any suggestion on how to force the dist function to strip down the matrix into smaller vectors? > > > Thank you in advance for your attention and for any feedback. > > All the best, Marco > > > -- > Marco Manca, MD > University of Maastricht > Faculty of Health, Medicine and Life Sciences (FHML) > Cardiovascular Research Institute (CARIM) > > Mailing address: PO Box 616, 6200 MD Maastricht (The Netherlands) > Visiting address: Experimental Vascular Pathology group, Dept of Pathology - Room5.08, Maastricht University Medical Center, P. Debeijelaan 25, 6229 HX Maastricht > > E-mail: m.manca at path.unimaas.nl > Office telephone: +31(0)433874633 > Personal mobile: +31(0)626441205 > Twitter: @markomanka > > > ******************************************************************** ************************************************* > > This email and any files transmitted with it are confide...{{dropped:15}} > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor >
ADD REPLY
0
Entering edit mode
Hi Marco, I just checked the page I gave you the link to and it appears that the options there are either i386 or amd64. :-( Maybe you'll need to compile from the source (the r-sig-debian folks will have the answer for sure). As you probably noticed, what you want to achieve is .Machine[["sizeof.pointer"]] == 8. b On Fri, Apr 16, 2010 at 8:04 PM, Manca Marco (PATH) <m.manca at="" path.unimaas.nl=""> wrote: > > Dear Benilton, > > thank you for the prompt reply. > > I suspect you are right. R had just been installed from the Canonical repository on this machine and it was a 32bit edition. > > Thank you for your suggestion and for pointing out the 64bit repositories. > > Just for the sake of completeness at this point, since you alread solved the puzzle, I attach the output of the command you suggested: > >> .Machine[["sizeof.pointer"]] > [1] 4 > > > All the best, Marco > > > -- > Marco Manca, MD > University of Maastricht > Faculty of Health, Medicine and Life Sciences (FHML) > Cardiovascular Research Institute (CARIM) > > Mailing address: PO Box 616, 6200 MD Maastricht (The Netherlands) > Visiting address: Experimental Vascular Pathology group, Dept of Pathology - Room5.08, ?Maastricht University Medical Center, P. Debeijelaan 25, 6229 ?HX Maastricht > > E-mail: m.manca at path.unimaas.nl > Office telephone: +31(0)433874633 > Personal mobile: +31(0)626441205 > Twitter: @markomanka > > > ******************************************************************** ************************************************* > > This email and any files transmitted with it are confidential and solely for the use of the intended recipient. > > It may contain material protected by privacy or attorney-client privilege. If you are not the intended recipient or the person responsible for > > delivering to the intended recipient, be advised that you have received this email in error and that any use is STRICTLY PROHIBITED. > > If you have received this email in error please notify us by telephone on +31626441205 Dr Marco MANCA > > ******************************************************************** ************************************************* > ________________________________________ > Da: Benilton Carvalho [beniltoncarvalho at gmail.com] > Inviato: venerd? 16 aprile 2010 18.47 > A: Manca Marco (PATH) > Cc: bioconductor mailing list > Oggetto: Re: [BioC] Memory and vector size management on linux 64bit > > what do you get when you run: > > .Machine[["sizeof.pointer"]] > > ? > > I'm really surprised by the "i486-pc-linux-gnu" bit from your > sessionInfo()... I'd expect something like x86_64, if you were running > a 64 bit version of R. > > Given that you're running Ubuntu, you're expected to follow the steps > as described by the page below: > > http://cran.ma.imperial.ac.uk/bin/linux/ubuntu/ > > b > > On Fri, Apr 16, 2010 at 5:30 PM, Manca Marco (PATH) > <m.manca at="" path.unimaas.nl=""> wrote: >> >> Dear fellow bioconductors, >> >> good afternoon. >> >> I am encountering an error concerning the allocations of vectors bigger than a certain size. My problem is that said size is far below the amount of RAM I have installed on the system. >> >> Following some previous threads on the topic I have at first thought that my RAM could have been temporarily unavailable thus I have monitored the memory usage and the error message appeared when just 2,5Gb were in use out of the about 7 Gb available. >> >> The system is running linux Ubuntu Hardy Heron 64bit, and it sports a Xeon CPU and 8Gb of RAM. >> >> Following I am pasting my code and my sessionInfo() >> >> # Charging my microArray data (44 human whole genome by Illumina) >>>library(lumi) >>>fileName <- "MyExperiment_no_32_no_tech_duplos.csv"; >>>library(lumiHumanAll.db) >>>Data.Immature <- lumiR(fileName, lib="lumiHumanAll.db"); >>>Data <- lumiExpresso(Data.Immature, QC.evaluation=TRUE); >> >> # Extract expression data from lumi object: >>>Expression <- exprs(Data) >>>names(Expression) <- Data at phenoData@data$sampleID >> >> # Calculate distance matrix for cluster analysis >>>distance=dist(Expression, method="euclidean") >> Error: cannot allocate vector of size 1.8 Gb >> >>> sessionInfo() >> R version 2.10.1 (2009-12-14) >> i486-pc-linux-gnu >> >> locale: >> ?[1] LC_CTYPE=en_US.UTF-8 ? ? ? LC_NUMERIC=C >> ?[3] LC_TIME=en_US.UTF-8 ? ? ? ?LC_COLLATE=en_US.UTF-8 >> ?[5] LC_MONETARY=C ? ? ? ? ? ? ?LC_MESSAGES=en_US.UTF-8 >> ?[7] LC_PAPER=en_US.UTF-8 ? ? ? LC_NAME=C >> ?[9] LC_ADDRESS=C ? ? ? ? ? ? ? LC_TELEPHONE=C >> [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C >> >> attached base packages: >> [1] stats ? ? graphics ?grDevices utils ? ? datasets ?methods ? base >> >> other attached packages: >> ?[1] lumiHumanAll.db_1.8.1 org.Hs.eg.db_2.3.6 ? ?lumi_1.12.4 >> ?[4] MASS_7.3-5 ? ? ? ? ? ?RSQLite_0.8-3 ? ? ? ? DBI_0.2-5 >> ?[7] preprocessCore_1.8.0 ?mgcv_1.6-1 ? ? ? ? ? ?affy_1.24.2 >> [10] annotate_1.24.1 ? ? ? AnnotationDbi_1.8.1 ? Biobase_2.6.1 >> >> loaded via a namespace (and not attached): >> [1] affyio_1.14.0 ? ? ?grid_2.10.1 ? ? ? ?lattice_0.18-3 ? ? Matrix_0.999375-37 >> [5] nlme_3.1-96 ? ? ? ?tools_2.10.1 ? ? ? xtable_1.5-6 >> >> >> >> Reading this page ( http://stat.ethz.ch/R-manual/R-patched/library/base/html/Memory.html ) I have come to hypothesize that there could be some vector size limit indipendent from the RAM availability, but I wonder whether it is true on a 64bit machine and how ?could I circumvent ?the problem: >> >> 1) any suggestion on how to modify the vector size threshold (if it exists)? >> >> 2) any suggestion on how to force the dist function to strip ?down the matrix into smaller vectors? >> >> >> Thank you in advance for your attention and for any feedback. >> >> All the best, Marco >> >> >> -- >> Marco Manca, MD >> University of Maastricht >> Faculty of Health, Medicine and Life Sciences (FHML) >> Cardiovascular Research Institute (CARIM) >> >> Mailing address: PO Box 616, 6200 MD Maastricht (The Netherlands) >> Visiting address: Experimental Vascular Pathology group, Dept of Pathology - Room5.08, ?Maastricht University Medical Center, P. Debeijelaan 25, 6229 ?HX Maastricht >> >> E-mail: m.manca at path.unimaas.nl >> Office telephone: +31(0)433874633 >> Personal mobile: +31(0)626441205 >> Twitter: @markomanka >> >> >> ******************************************************************* ************************************************** >> >> This email and any files transmitted with it are confide...{{dropped:15}} >> >> _______________________________________________ >> Bioconductor mailing list >> Bioconductor at stat.math.ethz.ch >> https://stat.ethz.ch/mailman/listinfo/bioconductor >> Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor >> >
ADD REPLY

Login before adding your answer.

Traffic: 525 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6