Dear Friends, I am interested in finding the consensus sequence of Transcription factor binding sites of list probe sequences. I found that cosmo would be the best choice. But while going through cosmo vignette, I did not understand selection criteria to choose sequences for calculation of background model. I mean to say, If probe sequences are of promoter region, should sequences to be selected to calculate the back ground model, also be promoter sequences of the same(and of the same organism)probes? Thanking you in anticipation. Regards, Prashantha ###################################################################### Attention: This e-mail message is privileged and confidential. If you are not the intended recipient please delete the message and notify the sender. Any views or opinions presented are solely those of the author. ###################################################################### Please do not print this email unless it is absolutely necessary. The information contained in this electronic message and...{{dropped:12}}