DearTing-Yuan I found your answer about how can we calculate common genes from two files but i have also similar problem but different interest. I also have two .text files including Genebank accession numbers respectively. I want to find the genes with the different GB Acession numbers from between two .txt files rather than same GB accession. Thank you so much for your help. Amrit [[alternative HTML version deleted]]

Hi, On Jul 9, 2009, at 12:22 AM, amrit karki wrote: > DearTing-Yuan > I found your answer about how can we calculate common genes from two > files but i have also similar problem but different interest. I also > have two .text files including Genebank accession numbers > respectively. I want to find the genes with the different GB > Acession numbers from between two .txt files rather than same GB > accession. Thank you so much for your help. I'm not sure I get your question, but is this what you're after? R> file1 <- paste("Gene", LETTERS[1:10]) R> file2 <- paste("Gene", LETTERS[5:15]) R> file1 [1] "Gene A" "Gene B" "Gene C" "Gene D" "Gene E" "Gene F" "Gene G" "Gene H" "Gene I" "Gene J" > file2 [1] "Gene E" "Gene F" "Gene G" "Gene H" "Gene I" "Gene J" "Gene K" "Gene L" "Gene M" "Gene N" "Gene O" > c(setdiff(file1, file2), setdiff(file2, file1)) [1] "Gene A" "Gene B" "Gene C" "Gene D" "Gene K" "Gene L" "Gene M" "Gene N" "Gene O" You can then use the names of the genes in your "difference" set to find the line in the respective files that differ (I guess this is what you want?) -steve -- Steve Lianoglou Graduate Student: Physiology, Biophysics and Systems Biology Weill Medical College of Cornell University Contact Info: http://cbio.mskcc.org/~lianos