On 26/6/09 7:00 PM, Sean Davis wrote: > Hi, Gad. I'm not sure what your goal is for looking for such genes, but > I think it likely that nearly all genes undergo alternative splicing > under the right conditions, so any gene that has multiple transcripts in > a database like RefSeq (or Ensembl) is likely to be a viable candidate. > See here for details, as an example. > > http://www.nature.com/nature/journal/v456/n7221/full/nature07509.html > > Hope that helps. > > Sean > Thank for the reference, Sean. My intention was to find which genes on an Affymetrix microarray are known to have multiple protein isoforms, in order to decide what to do with the issue of having multiple probesets per gene. Some probesets have very different expression patterns and it doesn't really make sense to consider them as belonging to one gene. Cheers, Gad -- Gad Abraham MEng Student, Dept. CSSE and NICTA The University of Melbourne Parkville 3010, Victoria, Australia email: gabraham at csse.unimelb.edu.au web: http://www.csse.unimelb.edu.au/~gabraham