apologies for those already on the CSSE list ... but might be of interest. oh, and presumably the "L5 meeting room" means this: http://wwwgenome.csse.unimelb.edu.au/taxonomy/term/5 m. Begin forwarded message: > From: Justin Bedo <justin.bedo at="" nicta.com.au=""> > Date: 15 June 2009 2:07:48 PM > To: genomics-research at csse.unimelb.edu.au > Subject: Presentation 19th June > > Dear all, > > This week's presentation will be give by two guests, Enes Makalic > and Daniel > Schmidt, from the Centre for MEGA Epidemiology. As usual, we are in > the L5 > meeting room and will start at 9am. > > Regards, > Justin > > Title: An Information Theoretic Approach to Analysing GWAS Data > > Abstract: Analysis of GWAS data often proceeds by performing many > independent > tests of association between genotypic data and phenotypes. A common > frequentist approach is to convert the data into contingency table > form, > compute suitable test statistics and correct for multiple testing > using a > Bonferroni-type procedure. This talk examines an alternative > approach based on > information theory in which there is no requirement for either a > `null' > hypothesis or specification of a significance level. Although not > strictly a > Bayesian method, the resulting procedure essentially yields posterior > probabilities over association that can be used as an extra tool in > interpreting GWAS data. ------------------------------ Mark Robinson, PhD (Melb) Epigenetics Laboratory, Garvan Bioinformatics Division, WEHI e: m.robinson at garvan.org.au e: mrobinson at wehi.edu.au p: +61 (0)3 9345 2628 f: +61 (0)3 9347 0852

Sorry, wrong email list. Ignore this message. Cheers, Mark On 15/06/2009, at 2:25 PM, Mark Robinson wrote: > > apologies for those already on the CSSE list ... but might be of > interest. > > oh, and presumably the "L5 meeting room" means this: > http://wwwgenome.csse.unimelb.edu.au/taxonomy/term/5 > > m. > > Begin forwarded message: > >> From: Justin Bedo <justin.bedo at="" nicta.com.au=""> >> Date: 15 June 2009 2:07:48 PM >> To: genomics-research at csse.unimelb.edu.au >> Subject: Presentation 19th June >> >> Dear all, >> >> This week's presentation will be give by two guests, Enes Makalic >> and Daniel >> Schmidt, from the Centre for MEGA Epidemiology. As usual, we are in >> the L5 >> meeting room and will start at 9am. >> >> Regards, >> Justin >> >> Title: An Information Theoretic Approach to Analysing GWAS Data >> >> Abstract: Analysis of GWAS data often proceeds by performing many >> independent >> tests of association between genotypic data and phenotypes. A common >> frequentist approach is to convert the data into contingency table >> form, >> compute suitable test statistics and correct for multiple testing >> using a >> Bonferroni-type procedure. This talk examines an alternative >> approach based on >> information theory in which there is no requirement for either a >> `null' >> hypothesis or specification of a significance level. Although not >> strictly a >> Bayesian method, the resulting procedure essentially yields posterior >> probabilities over association that can be used as an extra tool in >> interpreting GWAS data. > > ------------------------------ > Mark Robinson, PhD (Melb) > Epigenetics Laboratory, Garvan > Bioinformatics Division, WEHI > e: m.robinson at garvan.org.au > e: mrobinson at wehi.edu.au > p: +61 (0)3 9345 2628 > f: +61 (0)3 9347 0852 > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor ------------------------------ Mark Robinson, PhD (Melb) Epigenetics Laboratory, Garvan Bioinformatics Division, WEHI e: m.robinson at garvan.org.au e: mrobinson at wehi.edu.au p: +61 (0)3 9345 2628 f: +61 (0)3 9347 0852