Hi, I'm comparing the response of two viral strains to their host environments over a timecourse. Viral RNA abundance is measured at 0, 0.5, 1, 2, 4, 6, 18 and 24 hours post-infection. I am looking for procedures that will identify viral homologues in the two strains that show differential expression. For example, consider gene A1 in strain 1 and its homologue A2 in strain 2. I need a procedure that can identify whether the abundance profile of A1 is significantly different from that of A2 over the timecourse. TIA, Anjan -- =========================================== anjan purkayastha, phd bioinformatics analyst whitehead institute for biomedical research nine cambridge center cambridge, ma 02142 purkayas [at] wi [dot] mit [dot] edu 703.740.6939